Home Supplements How We Rate Blog
Panax ginseng

Ginseng

Research reviewed: Up until 03/2026

Ginseng (Panax ginseng) is a dietary supplement with 14 published peer-reviewed studies involving 1,340 participants, researched for Energy & Fatigue, Cognitive Function, Immune Support.

14
Studies
1,340
Participants
1996–2025
Research Span

Evidence at a Glance

Strength is scored by study design, sample size, study type, and outcomes

Overall: Very Strong Evidence

Energy & Fatigue

Strong
5 studies 5 of 5 positive 611 participants

Cognitive Function

Strong
4 studies 4 of 4 positive 407 participants

Immune Support

Strong
5 studies 3 of 5 positive 237 participants

Research Visualised

Visual breakdown of the clinical data.

Study Quality Breakdown

What types of studies were conducted

11/14
Randomised
11/14
Double-Blind
10/14
Placebo-Controlled

Participants Per Study

Larger samples = more reliable results

Study 1 (2013)
364
Study 2 (2022)
0
Study 3 (2025)
20
Study 4 (2023)
0
Study 5 (1996)
227
Study 6 (2020)
90
Study 7 (2024)
0
Study 8 (2008)
61

Research Timeline

When the studies were published

1
1996
1
2000
2
2002
2
2008
2
2012
1
2013
1
2020
1
2022
1
2023
1
2024
1
2025

All Studies

Detailed breakdown of each trial. Click to expand.

Energy & Fatigue

1

To investigate the effect of Panax ginseng on fatigue in cancer survivors

2013 364 participants 8 weeks 2000 mg/day
Human Study RCT Double-Blind Placebo Positive

Study Type

Randomised, double-blind, placebo-controlled

Purpose

To investigate the effect of Panax ginseng on fatigue in cancer survivors

Dose

2000 mg/day

Participants

364 cancer survivors

Duration

8 weeks

Results

Significant improvement in fatigue scores vs placebo (p<0.003). General fatigue subscale improved by 14 points vs 8.8 in placebo group.

How They Measured It

MFSI-SF fatigue scale

Read full study
2

To assess efficacy of ginseng for fatigue in randomised clinical trials

2022 ? participants Various Various
Human Study Positive

Study Type

Systematic review and meta-analysis

Purpose

To assess efficacy of ginseng for fatigue in randomised clinical trials

Dose

Various

Participants

Pooled from multiple RCTs

Duration

Various

Results

Ginseng significantly reduced fatigue across multiple conditions vs placebo (SMD -0.67, p<0.01).

How They Measured It

Standardised fatigue scales across RCTs

Read full study
3

To investigate acute effects of wild ginseng extract on exercise performance, cognitive function and fatigue

2025 20 participants Single acute dose crossover 2000 mg single dose
Human Study RCT Double-Blind Positive

Study Type

Randomised, double-blind, crossover

Purpose

To investigate acute effects of wild ginseng extract on exercise performance, cognitive function and fatigue

Dose

2000 mg single dose

Participants

20 healthy adults

Duration

Single acute dose crossover

Results

Ginseng significantly improved endurance performance, cognitive scores, and reduced fatigue vs placebo.

How They Measured It

Exercise capacity (VO2max), cognitive tests, fatigue VAS

Read full study
4

To evaluate ginseng and ginseng herbal formulas for symptomatic management of fatigue

2023 ? participants Various Various
Human Study Positive

Study Type

Systematic review and meta-analysis

Purpose

To evaluate ginseng and ginseng herbal formulas for symptomatic management of fatigue

Dose

Various

Participants

Multiple RCTs pooled

Duration

Various

Results

Ginseng formulas significantly reduced fatigue, particularly in cancer-related and idiopathic fatigue.

How They Measured It

Fatigue scales, meta-analytic methods

Read full study
5

To assess ginseng supplementation for influenza vaccination response

1996 227 participants 12 weeks 100 mg twice daily ginseng extract
Human Study RCT Double-Blind Placebo Positive

Study Type

Randomised, double-blind, placebo-controlled

Purpose

To assess ginseng supplementation for influenza vaccination response

Dose

100 mg twice daily ginseng extract

Participants

227 healthy adults

Duration

12 weeks

Results

Ginseng group had significantly higher antibody titres and lower incidence of influenza vs placebo.

How They Measured It

Antibody titres post-vaccination, flu incidence

Read full study

Cognitive Function

6

To investigate the cognition-enhancing effect of Panax ginseng in volunteers with mild cognitive impairment

2020 90 participants 24 weeks 4500 mg/day Korean red ginseng
Human Study RCT Double-Blind Placebo Positive

Study Type

Randomised, double-blind, placebo-controlled

Purpose

To investigate the cognition-enhancing effect of Panax ginseng in volunteers with mild cognitive impairment

Dose

4500 mg/day Korean red ginseng

Participants

90 Korean volunteers with mild cognitive impairment

Duration

24 weeks

Results

Significant improvement in ADAS-cog and attention scores vs placebo (p<0.01).

How They Measured It

MMSE, ADAS-cog, cognitive battery

Read full study
7

To systematically evaluate the effects of ginseng on cognitive function improvement via RCTs

2024 ? participants Various Various
Human Study Positive

Study Type

Systematic review and meta-analysis

Purpose

To systematically evaluate the effects of ginseng on cognitive function improvement via RCTs

Dose

Various

Participants

Multiple RCTs pooled

Duration

Various

Results

Ginseng supplementation significantly improved multiple cognitive domains including attention and memory.

How They Measured It

Cognitive performance tests, meta-analysis

Read full study
8

To assess effects of Korean red ginseng on cognitive function in Alzheimer's disease patients

2008 61 participants 12 weeks 4500 mg/day
Human Study RCT Double-Blind Placebo Positive

Study Type

Randomised, double-blind, placebo-controlled

Purpose

To assess effects of Korean red ginseng on cognitive function in Alzheimer's disease patients

Dose

4500 mg/day

Participants

61 Alzheimer's disease patients

Duration

12 weeks

Results

Significant improvements in ADAS-cog and MMSE scores vs placebo (p=0.032 and p=0.008).

How They Measured It

ADAS-cog, MMSE

Read full study
9

To assess Panax ginseng effect on cognitive performance in young healthy adults

2002 256 participants 8 days crossover 200 mg or 400 mg standardised extract
Human Study RCT Double-Blind Placebo Positive

Study Type

Randomised, double-blind, placebo-controlled

Purpose

To assess Panax ginseng effect on cognitive performance in young healthy adults

Dose

200 mg or 400 mg standardised extract

Participants

256 healthy volunteers

Duration

8 days crossover

Results

400 mg dose significantly improved speed of attention and quality of memory vs placebo.

How They Measured It

Serial subtraction, Corsi Blocks, Stroop task

Read full study

Immune Support

10

To evaluate Korean red ginseng on immune cell function in healthy adults

2012 39 participants 8 weeks 1800 mg/day Korean red ginseng
Human Study RCT Double-Blind Placebo Positive

Study Type

Randomised, double-blind, placebo-controlled

Purpose

To evaluate Korean red ginseng on immune cell function in healthy adults

Dose

1800 mg/day Korean red ginseng

Participants

39 healthy adults

Duration

8 weeks

Results

Significant enhancement of NK cell activity and T-cell immune response vs placebo.

How They Measured It

NK cell activity, T-cell proliferation, cytokines

Read full study
11

To evaluate Korean red ginseng effect on blood pressure in hypertensive adults

2008 62 participants 8 weeks 5 g/day Korean red ginseng
Human Study RCT Double-Blind Placebo Positive

Study Type

Randomised, double-blind, placebo-controlled

Purpose

To evaluate Korean red ginseng effect on blood pressure in hypertensive adults

Dose

5 g/day Korean red ginseng

Participants

62 hypertensive adults

Duration

8 weeks

Results

Significant reduction in systolic BP (by 5.6 mmHg) vs placebo.

How They Measured It

Systolic and diastolic blood pressure

Read full study
12

To assess Panax ginseng effect on sexual function in men with erectile dysfunction

2002 45 participants 8 weeks 900 mg 3x daily Korean red ginseng
Human Study RCT Double-Blind Placebo Positive

Study Type

Randomised, double-blind, placebo-controlled

Purpose

To assess Panax ginseng effect on sexual function in men with erectile dysfunction

Dose

900 mg 3x daily Korean red ginseng

Participants

45 men with erectile dysfunction

Duration

8 weeks

Results

Korean red ginseng significantly improved IIEF scores and penile rigidity vs placebo (p<0.05).

How They Measured It

IIEF questionnaire

Read full study
13

To evaluate ginseng supplementation on menopausal symptoms in postmenopausal women

2012 72 participants 12 weeks 3 g/day red ginseng
Human Study RCT Double-Blind Placebo Positive

Study Type

Randomised, double-blind, placebo-controlled

Purpose

To evaluate ginseng supplementation on menopausal symptoms in postmenopausal women

Dose

3 g/day red ginseng

Participants

72 postmenopausal women

Duration

12 weeks

Results

Significant reduction in menopausal symptoms vs placebo; particularly improved hot flash frequency.

How They Measured It

Kupperman index, FSH, oestradiol

Read full study
14

To assess effects of Panax ginseng on blood glucose and insulin in patients with type 2 diabetes

2000 19 participants 12 weeks 2 g/day ginseng extract
Human Study RCT Double-Blind Placebo Positive

Study Type

Randomised, double-blind, placebo-controlled

Purpose

To assess effects of Panax ginseng on blood glucose and insulin in patients with type 2 diabetes

Dose

2 g/day ginseng extract

Participants

19 type 2 diabetic patients

Duration

12 weeks

Results

Ginseng reduced fasting blood glucose by 19% and HbA1c improved significantly vs placebo.

How They Measured It

Fasting blood glucose, HbA1c, insulin

Read full study

Frequently Asked Questions

Common questions about Ginseng research

What does the research say about Ginseng?

There are currently 14 peer-reviewed studies on Ginseng (Panax ginseng), involving 1,340 total participants. Research covers Energy & fatigue, Cognitive function, Immune support. The overall evidence strength is rated as Very Strong.

How strong is the evidence for Ginseng?

The evidence is currently rated as "Very Strong Evidence". This rating is based on study design quality (randomisation, blinding, placebo controls), sample sizes, study types (14 human studies), and reported outcomes.

What health goals has Ginseng been studied for?

Ginseng has been researched for: Energy & fatigue, Cognitive function, Immune support. Each area has its own body of evidence which you can explore in the study breakdowns above.

Are the studies on Ginseng based on human trials?

Yes, 14 out of 14 studies are human trials. Human trials carry more weight in our evidence scoring system.