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Serenoa repens

Saw Palmetto

Research reviewed: up until 05/2023

Saw Palmetto (Serenoa repens) is a dietary supplement with 7 published peer-reviewed studies involving 467 participants, researched for Hair loss, BPH Symptoms, Hair & Scalp Health.

7
Studies
467
Participants
1998–2025
Research Span

Evidence at a Glance

Strength is scored by study design, sample size, study type, and outcomes

Overall: Strong Evidence

Hair loss

Strong
4 studies 2 of 4 positive 467 participants

BPH Symptoms

Moderate
2 studies 0 of 2 positive 0 participants 1 human

Hair & Scalp Health

Moderate
1 study 1 of 1 positive 0 participants

Research Visualised

Visual breakdown of the clinical data.

Study Quality Breakdown

What types of studies were conducted

4/7
Randomised
2/7
Double-Blind
2/7
Placebo-Controlled

Participants Per Study

Larger samples = more reliable results

Study 1 (2020)
0
Study 1 (2012)
100
Study 2 (2025)
300
Study 3 (2024)
67
Study 1 (1998)
0
Study 2 (2000)
0
Study 4 (2025)
0

Research Timeline

When the studies were published

1
1998
1
2000
1
2012
1
2020
1
2024
2
2025

All Studies

Detailed breakdown of each trial. Click to expand.

Hair loss

1

To describe the effects of Saw Palmetto extract on hair loss conditions and its associated side effects. Intervention under study: Oral and topical supplements containing 100-320 mg/day Saw Palmetto Studies Reviewed: 5 randomised controlled trials, 3 prospective cohort studies, and 1 case report

2020
Human Study Mixed

Study Type

Systematic review

Purpose

To describe the effects of Saw Palmetto extract on hair loss conditions and its associated side effects. Intervention under study: Oral and topical supplements containing 100-320 mg/day Saw Palmetto Studies Reviewed: 5 randomised controlled trials, 3 prospective cohort studies, and 1 case report

Results

The systematic review found associations between saw palmetto supplements and positive effects on patients with androgenetic alopecia (male pattern hair loss) and telogen effluvium (temporary hair loss that usually happens after stress, a shock, or a traumatic event), such as improvements in hair quality by 60%, hair density, and hair count by 3.4 to 27%.

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1

To compare the effects of Serenoa repens (saw palmetto) with finasteride on treating male androgenetic alopecia

2012 100 participants 2 years 320 mg/day of saw palmetto or 1 mg/day finasteride per day
Human Study Mixed

Study Type

Clinical trial (Uncontrolled)

Purpose

To compare the effects of Serenoa repens (saw palmetto) with finasteride on treating male androgenetic alopecia

Dose

320 mg/day of saw palmetto or 1 mg/day finasteride per day

Participants

100 men aged 20 to 40 years

Duration

2 years

Results

The study found an association between that 320 mg/day of saw palmetto and an increase in crown hair growth in 38% of patients. 68% of those treated with finasteride noted an improvement.

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2

To evaluate the efficacy of Serenoa repens (saw palmetto) combined with alfuzosin versus alfuzosin alone in treating benign prostatic hyperplasia

2025 300 participants 12 months Serenoa repens hexanic extract 320 mg/day + Alfuzosin 10 mg/...
Human Study RCT Positive

Study Type

Phase III, randomized, multicenter RCT

Purpose

To evaluate the efficacy of Serenoa repens (saw palmetto) combined with alfuzosin versus alfuzosin alone in treating benign prostatic hyperplasia

Dose

Serenoa repens hexanic extract 320 mg/day + Alfuzosin 10 mg/day vs Alfuzosin 10 mg/day alone

Participants

300 treatment-naive men with moderate-to-severe LUTS (IPSS > 7), prostate volume > 30 cc

Duration

12 months

Results

Combination therapy of saw palmetto with alfuzosin was significantly more effective than alfuzosin alone for LUTS relief from month 3 onward, with greater improvements in nocturia and Qmax

How They Measured It

International Prostate Symptom Score (IPSS), maximum flow rate (Qmax), quality of life, sexual function (IIEF-5, MSHQ-Ej)

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3

To assess beneficial effects of saw palmetto fruit extract on urinary symptoms in healthy Japanese adults with lower urinary tract symptoms

2024 67 participants 12 weeks 320 mg saw palmetto extract daily
Human Study RCT Double-Blind Placebo Positive

Study Type

Randomized, double-blind, placebo-controlled RCT

Purpose

To assess beneficial effects of saw palmetto fruit extract on urinary symptoms in healthy Japanese adults with lower urinary tract symptoms

Dose

320 mg saw palmetto extract daily

Participants

67 healthy Japanese adults aged ≥50 years without BPH diagnosis

Duration

12 weeks

Results

Saw palmetto significantly decreased daytime urinary frequency and improved symptom bother score and quality of life

How They Measured It

Daytime urinary frequency, symptom bother score, quality of life assessment

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BPH Symptoms

1

To assess therapeutic efficacy and safety of saw palmetto extract for benign prostatic hyperplasia

1998 ? participants Various study periods Saw palmetto extract (160 mg twice daily)
Review/Other Mixed

Study Type

Systematic review

Purpose

To assess therapeutic efficacy and safety of saw palmetto extract for benign prostatic hyperplasia

Dose

Saw palmetto extract (160 mg twice daily)

Participants

Meta-analysis of multiple RCTs in men with BPH

Duration

Various study periods

Results

Saw palmetto extract improved urinary tract symptoms, nocturia, and urine flow in some populations. Peak urine flow improvements noted.

How They Measured It

Urinary tract symptoms, urine flow rate, prostate size

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2

To evaluate saw palmetto herbal blend in men with symptomatic benign prostatic hyperplasia

2000 ? participants Study period Saw palmetto herbal blend
Human Study RCT Double-Blind Placebo Mixed

Study Type

Randomised, double-blind, placebo-controlled trial

Purpose

To evaluate saw palmetto herbal blend in men with symptomatic benign prostatic hyperplasia

Dose

Saw palmetto herbal blend

Participants

Men with symptomatic BPH

Duration

Study period

Results

Saw palmetto blend showed some benefit for BPH symptoms in studied population.

How They Measured It

BPH symptoms, urinary function

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Hair & Scalp Health

4

To evaluate the safety and efficacy of a proprietary bioactive fatty acids extract from saw palmetto for promoting hair growth and reducing hair loss.

2025 ? participants 90 days Saw palmetto fatty acids extract 160 mg twice daily
Human Study RCT Positive

Study Type

Randomized Controlled Trial

Purpose

To evaluate the safety and efficacy of a proprietary bioactive fatty acids extract from saw palmetto for promoting hair growth and reducing hair loss.

Dose

Saw palmetto fatty acids extract 160 mg twice daily

Participants

Adults with self-perceived thinning hair

Duration

90 days

Results

Saw palmetto extract significantly increased hair count, hair thickness, and reduced hair shedding compared to baseline over 90 days.

How They Measured It

Hair count, hair thickness, global assessment of hair loss, patient satisfaction

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Frequently Asked Questions

Common questions about Saw Palmetto research

What does the research say about Saw Palmetto?

There are currently 7 peer-reviewed studies on Saw Palmetto (Serenoa repens), involving 467 total participants. Research covers Hair loss. The overall evidence strength is rated as Strong.

How strong is the evidence for Saw Palmetto?

The evidence is currently rated as "Strong Evidence". This rating is based on study design quality (randomisation, blinding, placebo controls), sample sizes, study types (6 human studies), and reported outcomes.

What health goals has Saw Palmetto been studied for?

Saw Palmetto has been researched for: Hair loss. Each area has its own body of evidence which you can explore in the study breakdowns above.

Are the studies on Saw Palmetto based on human trials?

Yes, 6 out of 7 studies are human trials. Human trials carry more weight in our evidence scoring system.