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Matricaria chamomilla

Chamomile

Chamomile (Matricaria chamomilla) is a dietary supplement with 4 published peer-reviewed studies involving 267 participants, researched for Sleep.

4
Studies
267
Participants
2015–2022
Research Span

Evidence at a Glance

Strength is scored by study design, sample size, study type, and outcomes

Overall: Strong Evidence

Sleep

Strong
4 studies 3 of 4 positive 267 participants

Research Visualised

Visual breakdown of the clinical data.

Study Quality Breakdown

What types of studies were conducted

2/4
Randomised
0/4
Double-Blind
0/4
Placebo-Controlled

Participants Per Study

Larger samples = more reliable results

Study 1 (2022)
50
Study 2 (2017)
60
Study 3 (2017)
77
Study 4 (2015)
80

Research Timeline

When the studies were published

1
2015
2
2017
1
2022

All Studies

Detailed breakdown of each trial. Click to expand.

Sleep

1

To investigate the effects of chamomile extract on melatonin levels in subjects suffering from insomnia and anxiety.

2022 50 participants 60 days 15 ml/day of chamomile extract
Human Study Positive

Study Type

Clinical trial (uncontrolled)

Purpose

To investigate the effects of chamomile extract on melatonin levels in subjects suffering from insomnia and anxiety.

Dose

15 ml/day of chamomile extract

Participants

50 male and female participants, aged 18-60 years

Duration

60 days

Results

The researchers observed a significant increase in melatonin levels was observed from 0.17 ng/mL before treatment to 0.55 ng/mL after chamomile extract treatment for 60 days. Melatonin is a hormone which helps regulate sleep. The researchers also observed significant decreases in triglyceride (a type of fat found in the blood) and cholesterol levels.

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2

To evaluate the effects of chamomile extract on sleep quality among elderly people. Research has shown that insomnia tends to be more common as people age.

2017 60 participants 28 days 400 mg/day of chamomile extract (2 x 200 mg capsules) or pla...
Human Study RCT Positive

Study Type

Single-blind, randomised, controlled clinical trial

Purpose

To evaluate the effects of chamomile extract on sleep quality among elderly people. Research has shown that insomnia tends to be more common as people age.

Dose

400 mg/day of chamomile extract (2 x 200 mg capsules) or placebo (wheat flour capsules)

Participants

60 men and women with an average age of 70 years

Duration

28 days

Results

At the beginning of the study, participants in both the treatment and placebo groups had poor sleep quality. However, after 28 days of treatment, those taking chamomile extract capsules reported a significant improvement in their sleep quality compared to the placebo group. Given that sleep problems are common in older adults and many sleep medications may have harmful side effects, the authors recommended chamomile extract as a safe way to help improve sleep in the elderly.

How They Measured It

Sleep quality was assessed by interviewing participants at four time points: before the treatment started, two weeks into it, right after it finished, and two weeks after it ended.

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3

To determine the effect of chamomile extract on sleep quality in elderly people admitted to nursing homes

2017 77 participants 4 weeks 400 mg/day of chamomile extract (2 x 200 mg capsules) or con...
Human Study Positive

Study Type

Quasi-experimental clinical trial

Purpose

To determine the effect of chamomile extract on sleep quality in elderly people admitted to nursing homes

Dose

400 mg/day of chamomile extract (2 x 200 mg capsules) or control (no intervention)

Participants

77 men and women with an average age of 74 years

Duration

4 weeks

Results

Results of this study showed an association between 4 weeks consumption of chamomile extract and significant improvements in sleep quality.

How They Measured It

Sleep quality was assessed using a self-reported questionnaire which measures subjective sleep quality.

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4

To evaluate the effects of chamomile tea on sleep quality, fatigue, and depression in postpartum women

2015 80 participants 2 weeks 2 g/day of chamomile dried flowers (in one tea bag steeped i...
Human Study RCT Mixed

Study Type

Single-blind, randomised, controlled clinical trial

Purpose

To evaluate the effects of chamomile tea on sleep quality, fatigue, and depression in postpartum women

Dose

2 g/day of chamomile dried flowers (in one tea bag steeped in 300 ml hot water for 10-15 minutes)

Participants

80 postnatal women with an average age of 33 years (72 completed the study)

Duration

2 weeks

Results

Postnatal women who drank chamomile tea for 2 weeks saw a noticeable improvement in their sleep problems and symptoms of depression. These benefits were limited to the immediate term meaning, the effects only lasted while they were drinking the tea and did not continue once they stopped.

How They Measured It

Sleep quality, fatigue, and depression were assessed using standardised self-reported questionnaires that measured subjective sleep quality, postpartum depression, and perceived fatigue.

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Frequently Asked Questions

Common questions about Chamomile research

What does the research say about Chamomile?

There are currently 4 peer-reviewed studies on Chamomile (Matricaria chamomilla), involving 267 total participants. Research covers Sleep. The overall evidence strength is rated as Strong.

How strong is the evidence for Chamomile?

The evidence is currently rated as "Strong Evidence". This rating is based on study design quality (randomisation, blinding, placebo controls), sample sizes, study types (4 human studies), and reported outcomes.

What health goals has Chamomile been studied for?

Chamomile has been researched for: Sleep. Each area has its own body of evidence which you can explore in the study breakdowns above.

Are the studies on Chamomile based on human trials?

Yes, 4 out of 4 studies are human trials. Human trials carry more weight in our evidence scoring system.