Magnesium Oxide
Research reviewed: updated 08/24
Magnesium Oxide (MgO) is a dietary supplement with 2 published peer-reviewed studies involving 91 participants, researched for General, Sleep.
Evidence at a Glance
Strength is scored by study design, sample size, study type, and outcomes
General
ModerateSleep
ModerateResearch Visualised
Visual breakdown of the clinical data.
Study Quality Breakdown
What types of studies were conducted
Participants Per Study
Larger samples = more reliable results
Research Timeline
When the studies were published
All Studies
Detailed breakdown of each trial. Click to expand.
General
To examine the effects of oral magnesium supplementation on blood pressure in patients with essential hypertension, a condition where a person has high blood pressure in their arteries without any specific identifiable cause.
Study Type
Single-arm non-blinded intervention study
Purpose
To examine the effects of oral magnesium supplementation on blood pressure in patients with essential hypertension, a condition where a person has high blood pressure in their arteries without any specific identifiable cause.
Dose
300 mg/day of oral magnesium-oxide supplementation
Participants
48 men and women with essential hypertension
Duration
1 month
Results
After taking magnesium supplements, both systolic (upper value of BP reading) and diastolic (lower value of BP reading) blood pressures significantly decreased. On average, systolic pressure significantly dropped from 139.7 to 130.8 mmHg, and diastolic pressure significantly decreased from 88.0 to 82.2 mmHg. Overall, results suggest that magnesium supplements may help lower blood pressure.
Sleep
To investigate the effect of magnesium supplementation on insomnia in elderly.
Study Type
Randomised, double-blind, placebo-controlled trial
Purpose
To investigate the effect of magnesium supplementation on insomnia in elderly.
Dose
500 mg/d elemental magnesium (2 x 250 mg tablets) or placebo
Participants
43 men and women with an average age of 65 years
Duration
8 weeks
Results
The researchers observed that participants who took magnesium supplements had significant improvements compared to the placebo group. These included significantly longer sleep time, better sleep efficiency, higher levels of serum renin and melatonin, and a significant decrease in insomnia severity, time to fall asleep, and stress levels. They also observed trends in reduced early morning awakenings and increased magnesium levels.
How They Measured It
Insomnia was assessed using the Insomnia Severity Index (ISI), a seven-item questionnaire measuring sleep difficulties and satisfaction. Participants also kept daily sleep logs to track their sleep time.
Frequently Asked Questions
Common questions about Magnesium Oxide research
There are currently 2 peer-reviewed studies on Magnesium Oxide (MgO), involving 91 total participants. Research covers General, Sleep. The overall evidence strength is rated as Moderate.
The evidence is currently rated as "Moderate Evidence". This rating is based on study design quality (randomisation, blinding, placebo controls), sample sizes, study types (2 human studies), and reported outcomes.
Magnesium Oxide has been researched for: General, Sleep. Each area has its own body of evidence which you can explore in the study breakdowns above.
Yes, 2 out of 2 studies are human trials. Human trials carry more weight in our evidence scoring system.
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