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Zinc Monomethionine Aspartate

ZMA

Research reviewed: up until 05/2023

ZMA (Zinc Monomethionine Aspartate) is a dietary supplement with 1 published peer-reviewed study involving 27 participants, researched for Testosterone levels.

1
Studies
27
Participants
2000–2000
Research Span

Evidence at a Glance

Strength is scored by study design, sample size, study type, and outcomes

Overall: Moderate Evidence

Testosterone levels

Moderate
1 study 1 of 1 positive 27 participants

Research Visualised

Visual breakdown of the clinical data.

Study Quality Breakdown

What types of studies were conducted

1/1
Randomised
1/1
Double-Blind
0/1
Placebo-Controlled

Participants Per Study

Larger samples = more reliable results

Study 1 (2000)
27

Research Timeline

When the studies were published

1
2000

All Studies

Detailed breakdown of each trial. Click to expand.

Testosterone levels

1

To evaluate the effects of zinc, magnesium aspartate, and vitamin B6 (ZMA) on the anabolic hormones and muscle function in varsity football players

2000 27 participants 7 weeks 90 mg/day zinc monomethionine aspartate, 1350 mg/day magnesi...
Human Study RCT Double-Blind Positive

Study Type

Randomised, double-blind trial

Purpose

To evaluate the effects of zinc, magnesium aspartate, and vitamin B6 (ZMA) on the anabolic hormones and muscle function in varsity football players

Dose

90 mg/day zinc monomethionine aspartate, 1350 mg/day magnesium aspartate, and 31.5 mg/day vitamin B-6 (3 x ZMA capsule with 30 mg zinc monomethionine aspartate, 450 mg magnesium aspartate, and 10.5 mg vitamin nightly between dinner and bedtime) or placebo

Participants

27 varsity football players

Duration

7 weeks

Results

The study found an association between ZMA (zinc, magnesium aspartate, and vitamin B6) intake during the athletes' training period and a significant increase in total testosterone, rising from 567.9 to 752.2 ng/mL, while a decrease was observed in the placebo group, dropping from 588.8 to 526.8 ng/mL. Similarly, free testosterone significantly increased with ZMA (132.1 to 176.3 pg/mL) compared to the reduction observed in the placebo group (141.0 to 126.5 pg/mL). Additionally, the researchers observed a significant increase in insulin-like growth factor I (IGF-1, a hormone that promotes bone and tissue growth) in the ZMA group. The researchers also observed increases in quadriceps torque by 10% and quadriceps power by 12.7%-15.2% in the group taking ZMA, which is significantly greater than the change of -0.8% to 2.4% in quadriceps torque and 8.6% to 10.8% change in quadriceps power in the placebo group.

Read full study

Frequently Asked Questions

Common questions about ZMA research

What does the research say about ZMA?

There are currently 1 peer-reviewed studies on ZMA (Zinc Monomethionine Aspartate), involving 27 total participants. Research covers Testosterone levels. The overall evidence strength is rated as Moderate.

How strong is the evidence for ZMA?

The evidence is currently rated as "Moderate Evidence". This rating is based on study design quality (randomisation, blinding, placebo controls), sample sizes, study types (1 human study), and reported outcomes.

What health goals has ZMA been studied for?

ZMA has been researched for: Testosterone levels. Each area has its own body of evidence which you can explore in the study breakdowns above.

Are the studies on ZMA based on human trials?

Yes, 1 out of 1 studies are human trials. Human trials carry more weight in our evidence scoring system.