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Bovine Colostrum

Colostrum

Research reviewed: Up until 03/2026

Colostrum (Bovine Colostrum) is a dietary supplement with 11 published peer-reviewed studies involving 720 participants, researched for Immune Support, Athletic Performance, Gut Health.

11
Studies
720
Participants
1999–2024
Research Span

Evidence at a Glance

Strength is scored by study design, sample size, study type, and outcomes

Overall: Very Strong Evidence

Immune Support

Strong
4 studies 3 of 4 positive 376 participants

Athletic Performance

Moderate
3 studies 1 of 3 positive 126 participants

Gut Health

Strong
4 studies 2 of 4 positive 122 participants

Research Visualised

Visual breakdown of the clinical data.

Study Quality Breakdown

What types of studies were conducted

9/11
Randomised
8/11
Double-Blind
8/11
Placebo-Controlled

Participants Per Study

Larger samples = more reliable results

Study 1 (2001)
30
Study 2 (2014)
80
Study 3 (2021)
27
Study 4 (2020)
239
Study 5 (2001)
42
Study 6 (2002)
51
Study 7 (2018)
33
Study 8 (1999)
8

Research Timeline

When the studies were published

1
1999
2
2001
1
2002
1
2011
1
2014
1
2016
1
2018
1
2020
1
2021
1
2024

All Studies

Detailed breakdown of each trial. Click to expand.

Immune Support

1

To investigate bovine colostrum supplementation on salivary IgA and upper respiratory illness in athletes

2001 30 participants 12 weeks 60 g/day bovine colostrum
Human Study RCT Double-Blind Placebo Positive

Study Type

Randomised, double-blind, placebo-controlled

Purpose

To investigate bovine colostrum supplementation on salivary IgA and upper respiratory illness in athletes

Dose

60 g/day bovine colostrum

Participants

30 distance runners

Duration

12 weeks

Results

Colostrum group maintained salivary IgA levels and had significantly fewer URI days vs placebo.

How They Measured It

Salivary IgA, URI incidence and duration

Read full study
2

To assess bovine colostrum effects on upper respiratory illness in active males

2014 80 participants 10 weeks 10 g/day bovine colostrum
Human Study RCT Double-Blind Placebo Positive

Study Type

Randomised, double-blind, placebo-controlled

Purpose

To assess bovine colostrum effects on upper respiratory illness in active males

Dose

10 g/day bovine colostrum

Participants

80 active males

Duration

10 weeks

Results

Significant reduction in URI incidence and duration; improved immune cell function vs placebo.

How They Measured It

URI symptoms, duration, immune biomarkers

Read full study
3

To evaluate long-term bovine colostrum supplementation on immune system in young female basketball players

2021 27 participants 24 weeks 20 g/day bovine colostrum
Human Study RCT Positive

Study Type

Randomised, controlled

Purpose

To evaluate long-term bovine colostrum supplementation on immune system in young female basketball players

Dose

20 g/day bovine colostrum

Participants

27 elite female basketball players

Duration

24 weeks

Results

Significant improvements in immune cell function and reduced illness incidence vs control group.

How They Measured It

Neutrophil activity, IgA, NK cells, infection incidence

Read full study
4

To meta-analyse immunological outcomes of bovine colostrum in physically active people

2020 239 participants Various Various
Human Study Positive

Study Type

Systematic review and meta-analysis

Purpose

To meta-analyse immunological outcomes of bovine colostrum in physically active people

Dose

Various

Participants

239 across 10 RCTs

Duration

Various

Results

Colostrum significantly improved salivary IgA secretion rate and reduced illness episodes in athletes.

How They Measured It

Salivary IgA, immune cell counts, infection rates

Read full study

Athletic Performance

5

To evaluate bovine colostrum effect on lean muscle mass and strength in resistance-trained athletes

2001 42 participants 8 weeks 20 g/day bovine colostrum
Human Study RCT Double-Blind Placebo Mixed

Study Type

Randomised, double-blind, placebo-controlled

Purpose

To evaluate bovine colostrum effect on lean muscle mass and strength in resistance-trained athletes

Dose

20 g/day bovine colostrum

Participants

42 male athletes

Duration

8 weeks

Results

Greater increases in lean body mass (1.49 kg vs 0.95 kg) and strength vs whey protein group.

How They Measured It

Lean body mass (DXA), strength (1RM)

Read full study
6

To assess bovine colostrum on endurance performance and recovery in trained cyclists

2002 51 participants 8 weeks 20 g/day
Human Study RCT Double-Blind Placebo Positive

Study Type

Randomised, double-blind, placebo-controlled

Purpose

To assess bovine colostrum on endurance performance and recovery in trained cyclists

Dose

20 g/day

Participants

51 trained cyclists

Duration

8 weeks

Results

Significant improvement in sprint performance (6%) and time trial results vs whey protein placebo.

How They Measured It

Time trial performance, sprint power, recovery markers

Read full study
7

To assess in vivo immunity following prolonged exercise with bovine colostrum supplementation

2018 33 participants 5 weeks 25 g/day bovine colostrum
Human Study RCT Double-Blind Placebo Mixed

Study Type

Randomised, double-blind, placebo-controlled

Purpose

To assess in vivo immunity following prolonged exercise with bovine colostrum supplementation

Dose

25 g/day bovine colostrum

Participants

33 trained males

Duration

5 weeks

Results

Bovine colostrum attenuated exercise-induced immune suppression and maintained in vivo immune response.

How They Measured It

Delayed-type hypersensitivity, neutrophil function

Read full study

Gut Health

8

To evaluate bovine colostrum on gut permeability induced by NSAID use

1999 8 participants 5 days 125 mL/day bovine colostrum
Human Study RCT Double-Blind Placebo Positive

Study Type

Randomised, double-blind, placebo-controlled

Purpose

To evaluate bovine colostrum on gut permeability induced by NSAID use

Dose

125 mL/day bovine colostrum

Participants

8 healthy adults

Duration

5 days

Results

Bovine colostrum significantly prevented NSAID-induced increase in gut permeability vs placebo.

How They Measured It

Lactulose/mannitol ratio (gut permeability marker)

Read full study
9

To assess colostrum effect on exercise-induced gut permeability

2011 24 participants 14 days 20 g/day
Human Study RCT Double-Blind Placebo Positive

Study Type

Randomised, double-blind, placebo-controlled

Purpose

To assess colostrum effect on exercise-induced gut permeability

Dose

20 g/day

Participants

24 male runners

Duration

14 days

Results

Colostrum supplementation significantly attenuated exercise-induced gut permeability vs placebo.

How They Measured It

Gut permeability (lactulose/rhamnose ratio)

Read full study
10

To comprehensively analyse clinical trials on bovine colostrum in athletes

2024 ? participants Various Various
Human Study Mixed

Study Type

Systematic review

Purpose

To comprehensively analyse clinical trials on bovine colostrum in athletes

Dose

Various

Participants

Multiple trials

Duration

Various

Results

Colostrum consistently improved immune function, athletic performance, and gut barrier function across studies.

How They Measured It

Systematic review of immune, performance, and gut outcomes

Read full study
11

To evaluate bovine colostrum in reducing gastrointestinal symptoms in IBS patients

2016 90 participants 8 weeks 3 g/day bovine colostrum
Human Study RCT Double-Blind Placebo Positive

Study Type

Randomised, double-blind, placebo-controlled

Purpose

To evaluate bovine colostrum in reducing gastrointestinal symptoms in IBS patients

Dose

3 g/day bovine colostrum

Participants

90 IBS patients

Duration

8 weeks

Results

Significant reduction in bowel frequency, stool consistency scores and gut permeability vs placebo.

How They Measured It

IBS symptom score, stool consistency, gut permeability

Read full study

Frequently Asked Questions

Common questions about Colostrum research

What does the research say about Colostrum?

There are currently 11 peer-reviewed studies on Colostrum (Bovine Colostrum), involving 720 total participants. Research covers Immune support, Athletic performance, Gut health. The overall evidence strength is rated as Very Strong.

How strong is the evidence for Colostrum?

The evidence is currently rated as "Very Strong Evidence". This rating is based on study design quality (randomisation, blinding, placebo controls), sample sizes, study types (11 human studies), and reported outcomes.

What health goals has Colostrum been studied for?

Colostrum has been researched for: Immune support, Athletic performance, Gut health. Each area has its own body of evidence which you can explore in the study breakdowns above.

Are the studies on Colostrum based on human trials?

Yes, 11 out of 11 studies are human trials. Human trials carry more weight in our evidence scoring system.