BCAAs (Branched-Chain Amino Acids)
Research reviewed: Up until 03/2026
BCAAs (Branched-Chain Amino Acids) (L-Leucine, L-Isoleucine, L-Valine) is a dietary supplement with 35 published peer-reviewed studies involving 1,415 participants, researched for Muscle Building & Recovery, Athletic Performance, Muscle Protein Synthesis and 8 more areas.
Evidence at a Glance
Strength is scored by study design, sample size, study type, and outcomes
Muscle Building & Recovery
ModerateAthletic Performance
ModerateMuscle Protein Synthesis
ModerateLiver Disease Support
WeakSarcopenia & Muscle Mass in Elderly
ModerateMuscle Damage & Recovery Enhancement
WeakEndurance Performance & Fatigue
ModeratePost-Exercise Recovery & Adaptation
WeakCancer-Related Muscle Wasting & Cachexia
WeakSystematic reviews
WeakClinical trials
ModerateResearch Visualised
Visual breakdown of the clinical data.
Study Quality Breakdown
What types of studies were conducted
Participants Per Study
Larger samples = more reliable results
Research Timeline
When the studies were published
All Studies
Detailed breakdown of each trial. Click to expand.
Muscle Building & Recovery
To assess BCAAs on muscle protein synthesis and resistance exercise adaptations.
Study Type
Randomised, double-blind, placebo-controlled
Purpose
To assess BCAAs on muscle protein synthesis and resistance exercise adaptations.
Dose
BCAA 20g daily (leucine-enriched 2:1:1 ratio)
Participants
36 trained males
Duration
8 weeks
Results
BCAA supplementation significantly increased muscle protein synthesis rate and lean mass gains vs placebo. Leucine content was primary driver via mTOR pathway.
How They Measured It
Muscle protein synthesis rate (isotope tracer), lean mass, strength
To meta-analyse BCAA effects on exercise-induced muscle damage and DOMS.
Study Type
Systematic review and meta-analysis
Purpose
To meta-analyse BCAA effects on exercise-induced muscle damage and DOMS.
Dose
Various BCAA doses (typically 10-20g around exercise)
Participants
Multiple RCTs (700+ combined)
Duration
Various
Results
BCAAs significantly reduce exercise-induced muscle damage markers (CK) and perceived muscle soreness (DOMS). Attenuates strength loss after eccentric exercise.
How They Measured It
CK, muscle soreness scores, maximal strength recovery across RCTs
To evaluate BCAAs on muscle preservation during caloric restriction in wrestlers.
Study Type
Randomised, double-blind, placebo-controlled
Purpose
To evaluate BCAAs on muscle preservation during caloric restriction in wrestlers.
Dose
BCAA 14g daily during caloric restriction
Participants
25 competitive wrestlers
Duration
19 days
Results
BCAAs significantly preserved lean mass and strength while reducing fat mass. Nitrogen balance maintained positive vs negative in placebo group.
How They Measured It
Lean mass retention, fat mass, nitrogen balance, training performance
Athletic Performance
To investigate effects of BCAA supplementation on muscle protein synthesis and recovery following resistance exercise
Study Type
Randomized, double-blind, placebo-controlled trial
Purpose
To investigate effects of BCAA supplementation on muscle protein synthesis and recovery following resistance exercise
Dose
5 g BCAAs (2:1:1 ratio) post-workout
Participants
24 trained males
Duration
8 weeks with twice-weekly resistance training
Results
BCAA supplementation enhanced post-exercise muscle protein synthesis and reduced DOMS compared to placebo
How They Measured It
Muscle protein synthesis rates, DOMS (delayed onset muscle soreness), strength recovery
To evaluate effects of commercially available BCAA-based sports supplement on perceived exertion and performance in endurance cycling
Study Type
Randomized, double-blind, placebo-controlled trial
Purpose
To evaluate effects of commercially available BCAA-based sports supplement on perceived exertion and performance in endurance cycling
Dose
BCAA-alanine-carbohydrate supplement
Participants
Trained cyclists
Duration
Acute supplementation with performance testing
Results
BCAA-based supplement improved endurance cycling performance and reduced perceived exertion compared to placebo.
How They Measured It
Cycling performance, perceived exertion, fatigue markers
To evaluate muscle damage biomarkers and soreness following BCAA supplementation with exercise-induced muscle damage
Study Type
Systematic review and meta-analysis
Purpose
To evaluate muscle damage biomarkers and soreness following BCAA supplementation with exercise-induced muscle damage
Dose
BCAA supplementation (various doses and timing)
Participants
Meta-analysis of randomized trials
Duration
Various study periods
Results
BCAA supplementation showed a significant effect on reducing creatine kinase levels and muscle soreness biomarkers, with post-exercise timing being most effective.
How They Measured It
CK levels, muscle soreness, IL-6, CRP inflammatory markers
Muscle Protein Synthesis
To compare impact of BCAAs and BCAAs vs milk protein on myofibrillar protein synthesis in older males
Study Type
Double-blind, randomized trial
Purpose
To compare impact of BCAAs and BCAAs vs milk protein on myofibrillar protein synthesis in older males
Dose
6 g BCAA vs 6 g BCKA vs 30 g milk protein
Participants
Older adult males
Duration
Acute measurement post-consumption
Results
BCAA ingestion increased post-exercise stimulation of myofibrillar protein synthesis and mTORC1 signaling in older males.
How They Measured It
Myofibrillar protein synthesis rates, amino acid levels, mTORC1 signaling
To assess whether BCAAs supplementation attenuates muscle damage and soreness after resistance exercise
Study Type
Meta-analysis of randomized controlled trials
Purpose
To assess whether BCAAs supplementation attenuates muscle damage and soreness after resistance exercise
Dose
BCAA (various doses)
Participants
Meta-analysis of trained male subjects
Duration
Various study periods
Results
Mixed evidence: some studies showed BCAA reduced soreness, but effects variable depending on training status and dose.
How They Measured It
Muscle damage markers, soreness, performance
To evaluate sex-based effects of BCAA supplementation on strength training performance and body composition
Study Type
Randomized, double-blind, placebo-controlled trial
Purpose
To evaluate sex-based effects of BCAA supplementation on strength training performance and body composition
Dose
BCAA supplementation
Participants
Both male and female participants
Duration
Training intervention period
Results
BCAA supplementation improved muscle recovery and reduced fatigue in both sexes, with pronounced gender-specific results: women experienced greater reductions in DOMS while men achieved more significant strength gains.
How They Measured It
Muscle strength, body composition, muscle protein synthesis markers
Liver Disease Support
To evaluate impact of BCAAs on muscle mass, strength, liver function in sarcopenic patients with liver cirrhosis
Study Type
Randomized clinical trial (BCAAS Study)
Purpose
To evaluate impact of BCAAs on muscle mass, strength, liver function in sarcopenic patients with liver cirrhosis
Dose
BCAA supplementation
Participants
Sarcopenic patients with liver cirrhosis
Duration
Long-term follow-up
Results
BCAA supplementation maintained or improved muscle mass, liver function, and potentially survival outcomes in cirrhotic patients.
How They Measured It
Muscle mass, liver function tests, survival markers, quality of life
To evaluate the effectiveness of branched-chain amino acids for hepatic encephalopathy in people with cirrhosis
Study Type
Cochrane Systematic Review and Meta-analysis
Purpose
To evaluate the effectiveness of branched-chain amino acids for hepatic encephalopathy in people with cirrhosis
Dose
BCAA supplementation (oral and intravenous)
Participants
Meta-analysis of 16 randomized trials (827 participants)
Duration
Various study periods
Results
BCAA had a beneficial effect on hepatic encephalopathy (RR 0.73, 95% CI 0.61 to 0.88; high quality evidence). Oral BCAA was more effective than intravenous. No difference in mortality was found.
How They Measured It
Hepatic encephalopathy incidence, mortality, liver-related events
Sarcopenia & Muscle Mass in Elderly
To evaluate effects of branched-chain amino acid-rich supplementation on EWGSOP2 criteria for sarcopenia in older adults
Study Type
Systematic review and meta-analysis
Purpose
To evaluate effects of branched-chain amino acid-rich supplementation on EWGSOP2 criteria for sarcopenia in older adults
Dose
BCAA-rich supplementation (various doses)
Participants
Meta-analysis of 35 randomized controlled trials (elderly populations)
Duration
Various study periods
Results
BCAA-rich supplementation may have beneficial effects on muscle mass and strength in older people, though heterogeneity was high. Combined intervention with exercise was more effective.
How They Measured It
Muscle mass, muscle strength, physical performance
To evaluate BCAAs combined with exercise on physical function and quality of life in older adults
Study Type
Pilot randomized, double-blind, placebo-controlled trial
Purpose
To evaluate BCAAs combined with exercise on physical function and quality of life in older adults
Dose
BCAA supplementation
Participants
Older adults
Duration
Multiple weeks
Results
BCAAs combined with exercise improved physical performance, reduced fatigue and depressive symptoms compared to exercise alone.
How They Measured It
Physical performance tests, muscle strength, fatigue, depression
Muscle Damage & Recovery Enhancement
To evaluate the use of BCAAs to decrease delayed-onset muscle soreness (DOMS) after exercise-induced muscle damage
Study Type
Systematic review and meta-analysis
Purpose
To evaluate the use of BCAAs to decrease delayed-onset muscle soreness (DOMS) after exercise-induced muscle damage
Dose
BCAA supplementation (various doses and timing)
Participants
Meta-analysis of multiple RCTs
Duration
Various study periods
Results
BCAA post-exercise supplementation significantly reduced muscle soreness scores at 24h, 48h, 72h, and 96h after resistance training. BCAA reduced inflammatory markers (IL-6, CRP) and muscle damage markers.
How They Measured It
Muscle soreness scores, muscle damage markers (CK, LDH), recovery time
To evaluate timing of BCAA supplementation on muscle recovery after resistance training
Study Type
Randomized clinical trial
Purpose
To evaluate timing of BCAA supplementation on muscle recovery after resistance training
Dose
BCAA supplementation (pre- vs post-exercise)
Participants
Healthy males
Duration
Multiple training sessions
Results
Post-exercise BCAA supplementation was more effective than pre-exercise in alleviating DOMS symptoms and reducing inflammatory factors, though neuromuscular recovery was not significantly different.
How They Measured It
DOMS, inflammatory markers (IL-6, CRP), muscle damage markers, neuromuscular recovery
Endurance Performance & Fatigue
To evaluate effects of BCAA supplementation on endurance exercise performance and fatigue
Study Type
Randomized cross-over trial
Purpose
To evaluate effects of BCAA supplementation on endurance exercise performance and fatigue
Dose
BCAA supplementation (combined with arginine and citrulline)
Participants
Endurance-trained athletes
Duration
Acute supplementation with endurance testing
Results
BCAA supplementation (combined with arginine and citrulline) significantly improved 5000m and 10000m time trial performance and reduced exercise-induced fatigue in endurance runners.
How They Measured It
Time to exhaustion, exercise-induced fatigue, muscle damage biomarkers
To evaluate BCAA supplementation effects on substrate metabolism and fatigue during endurance exercise
Study Type
Double-blind, placebo-controlled cross-over study
Purpose
To evaluate BCAA supplementation effects on substrate metabolism and fatigue during endurance exercise
Dose
BCAA supplementation
Participants
Active young males
Duration
Acute supplementation with exercise
Results
Pre-exercise BCAA supplementation enhanced fat oxidation and carbohydrate metabolism, improved exercise efficiency, and significantly alleviated exercise-induced fatigue.
How They Measured It
Carbohydrate and fat oxidation, perceived exertion, fatigue markers
Post-Exercise Recovery & Adaptation
To assess whether BCAA supplementation attenuates muscle damage and soreness after resistance exercise in trained males
Study Type
Meta-analysis of randomized controlled trials
Purpose
To assess whether BCAA supplementation attenuates muscle damage and soreness after resistance exercise in trained males
Dose
BCAA (various doses)
Participants
Meta-analysis of trained male subjects
Duration
Various study periods
Results
Mixed evidence: some studies showed BCAA reduced soreness, but effects variable depending on training status and dose. Pre-trained individuals may benefit less than untrained.
How They Measured It
Muscle damage markers, soreness perception, performance recovery
Cancer-Related Muscle Wasting & Cachexia
To evaluate BCAA supplementation in patients with cancer-related cachexia and muscle wasting during treatment
Study Type
Systematic review and narrative analysis
Purpose
To evaluate BCAA supplementation in patients with cancer-related cachexia and muscle wasting during treatment
Dose
BCAA supplementation (various doses)
Participants
Cancer patients with cachexia/muscle wasting
Duration
Various study periods
Results
BCAA supplementation showed promise in cancer patients, with some studies reporting improved albumin concentrations and lean mass maintenance, though heterogeneity in outcomes was noted.
How They Measured It
Lean body mass, muscle strength, albumin levels, quality of life
To evaluate the role of leucine and BCAAs in attenuating muscle wasting in cancer cachexia
Study Type
Research review
Purpose
To evaluate the role of leucine and BCAAs in attenuating muscle wasting in cancer cachexia
Dose
BCAA/leucine supplementation
Participants
Experimental and clinical studies in cachexia
Duration
Various
Results
Leucine and BCAAs may attenuate muscle wasting through mTOR pathway activation and modulation of proteasomal degradation, though survival benefits in cancer patients remain unclear.
How They Measured It
Protein synthesis, protein degradation, mTOR pathway activation
Systematic reviews
To investigate the effects of BCAAs (Branched-Chain Amino Acids) in the effect of oral pure branched-chain amino acid supplementation on exercise performance and body composition: a systematic review.
Study Type
Systematic review
Purpose
To investigate the effects of BCAAs (Branched-Chain Amino Acids) in the effect of oral pure branched-chain amino acid supplementation on exercise performance and body composition: a systematic review.
Dose
1.5g
Participants
511 participants
Duration
Duration not specified
Results
, BCAA supplementation may reduce muscle soreness post-exercise, but evidence for improvements in strength, endurance, and body composition remains inconsistent. However, future studies should consider improving certain limitations such as implementing incremental doses, strict diets, and enrolling more participants with diverse backgrounds.
How They Measured It
See study for outcome measures
To investigate the effects of BCAAs (Branched-Chain Amino Acids) in exploring the metabolomics profile of frailty- a systematic review.
Study Type
Systematic review
Purpose
To investigate the effects of BCAAs (Branched-Chain Amino Acids) in exploring the metabolomics profile of frailty- a systematic review.
Dose
BCAAs (Branched-Chain Amino Acids) (dose not specified)
Participants
Participants not specified
Duration
Duration not specified
Results
Frailty is a multifaceted geriatric syndrome characterized by an increased vulnerability to stressful events. metabolomics studies are valuable tool for better understanding the underlying mechanisms of pathologic conditions. This review aimed to elucidate the metabolomics profile of frailty.
How They Measured It
See study for outcome measures
To investigate the effects of BCAAs (Branched-Chain Amino Acids) in serum branched amino acids and the risk of all-cause mortality: a meta-analysis and systematic review.
Study Type
Systematic review and meta-analysis
Purpose
To investigate the effects of BCAAs (Branched-Chain Amino Acids) in serum branched amino acids and the risk of all-cause mortality: a meta-analysis and systematic review.
Dose
BCAAs (Branched-Chain Amino Acids) (dose not specified)
Participants
Participants not specified
Duration
Duration not specified
Results
x2009;= 89.4% and P-heterogeneity < 0.001), leucine (I 2 = 87.8% and P-heterogeneity < 0.001), and valine (I 2 = 86.6% and P-heterogeneity < 0.001). Our results suggested that the serum BCAAs and its components, including isoleucine, leucine, and valine, were not associated with the risk of all-cause mortality.
How They Measured It
See study for outcome measures
To investigate the effects of BCAAs (Branched-Chain Amino Acids) in intravenous branched-chain amino acid administration for the acute treatment of hepatic encephalopathy: a systematic review and meta-analysis.
Study Type
Systematic review and meta-analysis
Purpose
To investigate the effects of BCAAs (Branched-Chain Amino Acids) in intravenous branched-chain amino acid administration for the acute treatment of hepatic encephalopathy: a systematic review and meta-analysis.
Dose
BCAAs (Branched-Chain Amino Acids) (dose not specified)
Participants
Participants not specified
Duration
Duration not specified
Results
and valine have been investigated as potential treatments to improve outcomes in patients with acute HE. However, the effectiveness of BCAA administration during the acute phase remains unclear. This study aimed to evaluate the effect of intravenous BCAA (IV-BCAA) treatment on clinical outcomes in patients with acute HE by systematically reviewing and analyzing randomized controlled trials (RCTs).
How They Measured It
See study for outcome measures
To investigate the effects of BCAAs (Branched-Chain Amino Acids) in dietary branched chain amino acids association with cancer and mortality: a systematic review and meta-analysis of observational studies.
Study Type
Systematic review and meta-analysis
Purpose
To investigate the effects of BCAAs (Branched-Chain Amino Acids) in dietary branched chain amino acids association with cancer and mortality: a systematic review and meta-analysis of observational studies.
Dose
BCAAs (Branched-Chain Amino Acids) (dose not specified)
Participants
Participants not specified
Duration
Duration not specified
Results
ne : 1.01, 95% CI: 0.84-1.21) and all-cause mortality (RR BCAA : 0.98, 95% CI: 0.73-1.32, RR Leucine : 1.02, 95% CI: 0.81-1.29, RR Isoleucine : 0.96, 95% CI: 0.73-1.27, RR Valine : 1.02, 95% CI: 0.79-1.32) were observed. Our findings showed no significant association between dietary BCAAs and its components with BC and digestive cancers, BC and digestive cancers mortality, and all-cause mortality.
How They Measured It
See study for outcome measures
To investigate the effects of BCAAs (Branched-Chain Amino Acids) in branched-chain amino acid supplements for sarcopenia in liver cirrhosis: a systematic review and meta-analysis.
Study Type
Systematic review and meta-analysis
Purpose
To investigate the effects of BCAAs (Branched-Chain Amino Acids) in branched-chain amino acid supplements for sarcopenia in liver cirrhosis: a systematic review and meta-analysis.
Dose
BCAAs (Branched-Chain Amino Acids) (dose not specified)
Participants
Participants not specified
Duration
Duration not specified
Results
Sarcopenia, a key aspect of malnutrition in liver cirrhosis (LC), affects 30-70% of LC patients. Given the inconsistent results from RCTs on branched-chain amino acids (BCAAs) for treating sarcopenia in LC, we conducted a systematic review and meta-analysis to assess the efficacy and safety of BCAAs for sarcopenia management in LC patients.
How They Measured It
See study for outcome measures
Clinical trials
To investigate the effects of BCAAs (Branched-Chain Amino Acids) in strain specific effects of probiotic supplementation on serum amino acid profiles in alzheimer's disease: a randomized, double blind, placebo controll
Study Type
Randomized, double-blind, placebo-controlled
Purpose
To investigate the effects of BCAAs (Branched-Chain Amino Acids) in strain specific effects of probiotic supplementation on serum amino acid profiles in alzheimer's disease: a randomized, double blind, placebo controll
Dose
BCAAs (Branched-Chain Amino Acids) (dose not specified)
Participants
60 participants
Duration
Duration not specified
Results
across all primary outcome measures. Probiotic supplementation, particularly with B. longum, significantly improved serum amino acid profiles in patients with mild to moderate Alzheimer's disease. These findings support the potential of specific probiotic strains to address metabolic imbalances in AD through gut-brain axis modulation. Trial Registration: IRCT number: 20210513051277N1 (2021-05-27).
How They Measured It
See study for outcome measures
To investigate the effects of BCAAs (Branched-Chain Amino Acids) in effects of branched-chain amino acids on changes in body composition during the recovery period following tonsillectomy.
Study Type
Randomized, double-blind, placebo-controlled
Purpose
To investigate the effects of BCAAs (Branched-Chain Amino Acids) in effects of branched-chain amino acids on changes in body composition during the recovery period following tonsillectomy.
Dose
BCAAs (Branched-Chain Amino Acids) (dose not specified)
Participants
Participants not specified
Duration
Duration not specified
Results
composition changes post-tonsillectomy. In oncology and digestive surgeries, the potential benefits of branched-chain amino acids (BCAAs) have been investigated; however, their effects on pharyngeal surgery remain unknown. Therefore, the aim of the present study was to investigate the body composition changes after tonsillectomy and to explore the potential benefits of branched-chain amino acids.
How They Measured It
See study for outcome measures
To investigate the effects of BCAAs (Branched-Chain Amino Acids) in amino acid composition of plant protein-enriched wheat biscuits differentially affects postprandial amino acid responses of overweight/obese compared
Study Type
Randomized, double-blind, placebo-controlled
Purpose
To investigate the effects of BCAAs (Branched-Chain Amino Acids) in amino acid composition of plant protein-enriched wheat biscuits differentially affects postprandial amino acid responses of overweight/obese compared
Dose
BCAAs (Branched-Chain Amino Acids) (dose not specified)
Participants
Participants not specified
Duration
Duration not specified
Results
s whether postprandial amino acid responses differ between normalweight (NW) and overweight/obese (OW) individuals following consumption of plant protein-enriched wheat biscuits with the same protein content but different protein composition. It highlights the importance of developing functional snack products with specific amino acid profile that could benefit individuals with overweight/obesity.
How They Measured It
See study for outcome measures
To investigate the effects of BCAAs (Branched-Chain Amino Acids) in supplementation with bacillus clausii ubbc-07 enhances circulating essential amino acids in young adults: a double-blind, randomized, controlled trial
Study Type
Clinical study
Purpose
To investigate the effects of BCAAs (Branched-Chain Amino Acids) in supplementation with bacillus clausii ubbc-07 enhances circulating essential amino acids in young adults: a double-blind, randomized, controlled trial
Dose
20 g
Participants
Participants not specified
Duration
60 days
Results
A significant improvement in circulating EAA levels in the probiotic group suggests an enhancement of protein absorption with Bacillus clausii UBBC-07 supplementation. The effect of BCAAs, which enhance muscle strength, is evident in the significant improvement in leg press and a trend towards improvement in deadlift and vertical jump in the probiotic group. This has positive implication
How They Measured It
See study for outcome measures
To investigate the effects of BCAAs (Branched-Chain Amino Acids) in post hoc analysis of a randomized placebo-controlled trial suggests potential visual benefits of branched-chain amino acids in retinitis pigmentosa.
Study Type
Randomized, double-blind, placebo-controlled
Purpose
To investigate the effects of BCAAs (Branched-Chain Amino Acids) in post hoc analysis of a randomized placebo-controlled trial suggests potential visual benefits of branched-chain amino acids in retinitis pigmentosa.
Dose
98 g
Participants
Participants not specified
Duration
78 weeks
Results
l point score (TPS) and MD in the TK-98 group. After covariate adjustment, TPS and MD reductions tended to be slower in the TK-98 group than in the placebo group. The eligibility screening visual-field test could be affected by psychological factors, such as patients' concentration or motivation, leading to better-than-usual screening test results and making them less appropriate as baseline data.
How They Measured It
See study for outcome measures
To investigate the effects of BCAAs (Branched-Chain Amino Acids) in branched-chain amino acid supplementation enhances substrate metabolism, exercise efficiency and reduces post-exercise fatigue in active young males.
Study Type
Randomized, double-blind, placebo-controlled
Purpose
To investigate the effects of BCAAs (Branched-Chain Amino Acids) in branched-chain amino acid supplementation enhances substrate metabolism, exercise efficiency and reduces post-exercise fatigue in active young males.
Dose
BCAAs (Branched-Chain Amino Acids) (dose not specified)
Participants
8 participants
Duration
Duration not specified
Results
This study shows the critical role of BCAAs during exercise in active males and finds that BCAA supplementation enhanced fat oxidation during the CLE, increased carbohydrate oxidation and exercise efficiency during the TTE, and reduced immediate post-exercise fatigue.
How They Measured It
See study for outcome measures
To investigate the effects of BCAAs (Branched-Chain Amino Acids) in high leucine branched-chain amino acids supplementation ameliorates quadriceps femoris muscle thickness reduction and attenuates interleukin-6 in crit
Study Type
Randomized, double-blind, placebo-controlled
Purpose
To investigate the effects of BCAAs (Branched-Chain Amino Acids) in high leucine branched-chain amino acids supplementation ameliorates quadriceps femoris muscle thickness reduction and attenuates interleukin-6 in crit
Dose
BCAAs (Branched-Chain Amino Acids) (dose not specified)
Participants
Participants not specified
Duration
Duration not specified
Results
ring the quadriceps femoris muscle thickness (QFMT). One significant contributing factor is inflammation, with interleukin-6 (IL-6) as one of the important markers. Branched-chain amino acids (BCAAs), especially leucine, enhance muscle protein synthesis, and reduce inflammation. This study examined the effects of high leucine BCAA supplementation on QFMT and IL-6 levels in critically ill patients.
How They Measured It
See study for outcome measures
To investigate the effects of BCAAs (Branched-Chain Amino Acids) in prospective randomized, placebo-controlled study: role of branched-chain amino acids infusion as adjunct therapy post-liver surgery for patients in th
Study Type
Randomized, double-blind, placebo-controlled
Purpose
To investigate the effects of BCAAs (Branched-Chain Amino Acids) in prospective randomized, placebo-controlled study: role of branched-chain amino acids infusion as adjunct therapy post-liver surgery for patients in th
Dose
BCAAs (Branched-Chain Amino Acids) (dose not specified)
Participants
Participants not specified
Duration
Duration not specified
Results
Several animal studies have shown that Branched-chain amino acids (BCAAs) may prevent acute liver injury, although its effects in humans are as yet undetermined. Thus the purpose of this study is to evaluate the impact of intravenous BCAAs infusion on liver profile post-liver surgery in the intensive care unit (ICU).
How They Measured It
See study for outcome measures
To investigate the effects of BCAAs (Branched-Chain Amino Acids) in consumption of a branched-chain amino acids-containing sports beverage during 21 km of running reduces dehydration, lowers muscle damage, and prevents
Study Type
Randomized, double-blind, placebo-controlled
Purpose
To investigate the effects of BCAAs (Branched-Chain Amino Acids) in consumption of a branched-chain amino acids-containing sports beverage during 21 km of running reduces dehydration, lowers muscle damage, and prevents
Dose
BCAAs (Branched-Chain Amino Acids) (dose not specified)
Participants
Participants not specified
Duration
Duration not specified
Results
The purpose of this study was to examine the acute effects of branched-chain amino acids (BCAAs)-containing electrolyte beverage (AE) on water-electrolyte balance, muscle damage, time to finish the final 5 km, and muscle strength compared to a standard commercially available carbohydrate-electrolyte sports beverage (CE), pure water (W), and no rehydration (N).
How They Measured It
See study for outcome measures
Frequently Asked Questions
Common questions about BCAAs (Branched-Chain Amino Acids) research
There are currently 35 peer-reviewed studies on BCAAs (Branched-Chain Amino Acids) (L-Leucine, L-Isoleucine, L-Valine), involving 1,415 total participants. Research covers Muscle Building & Recovery, Athletic Performance, Muscle Protein Synthesis and 8 more areas. The overall evidence strength is rated as Strong.
The evidence is currently rated as "Strong Evidence". This rating is based on study design quality (randomisation, blinding, placebo controls), sample sizes, study types (20 human studies), and reported outcomes.
BCAAs (Branched-Chain Amino Acids) has been researched for: Muscle Building & Recovery, Athletic Performance, Muscle Protein Synthesis, Liver Disease Support, Sarcopenia & Muscle Mass in Elderly, Muscle Damage & Recovery Enhancement, Endurance Performance & Fatigue, Post-Exercise Recovery & Adaptation, Cancer-Related Muscle Wasting & Cachexia, Systematic reviews, Clinical trials. Each area has its own body of evidence which you can explore in the study breakdowns above.
Yes, 20 out of 35 studies are human trials. Human trials carry more weight in our evidence scoring system.
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