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Triphala

Triphala

Research reviewed: Up until 03/2026

Triphala is a dietary supplement with 10 published peer-reviewed studies involving 720 participants, researched for Digestive & Gut Health, Antioxidant & Anti-inflammatory, Weight Management & Metabolic Health and 2 more areas.

10
Studies
720
Participants
2005–2022
Research Span

Evidence at a Glance

Strength is scored by study design, sample size, study type, and outcomes

Overall: Very Strong Evidence

Digestive & Gut Health

Strong
2 studies 2 of 2 positive 110 participants

Antioxidant & Anti-inflammatory

Strong
2 studies 2 of 2 positive 95 participants

Weight Management & Metabolic Health

Strong
2 studies 2 of 2 positive 135 participants

Oral Health

Strong
2 studies 2 of 2 positive 100 participants

Cancer Prevention & Immunity

Moderate
2 studies 1 of 2 positive 30 participants 1 human

Research Visualised

Visual breakdown of the clinical data.

Study Quality Breakdown

What types of studies were conducted

9/10
Randomised
6/10
Double-Blind
6/10
Placebo-Controlled

Participants Per Study

Larger samples = more reliable results

Study 1 (2017)
50
Study 2 (2019)
60
Study 3 (2014)
50
Study 4 (2018)
45
Study 5 (2012)
75
Study 6 (2011)
60
Study 7 (2005)
60
Study 8 (2010)
40

Research Timeline

When the studies were published

1
2005
1
2010
1
2011
1
2012
1
2014
1
2016
1
2017
1
2018
1
2019
1
2022

All Studies

Detailed breakdown of each trial. Click to expand.

Digestive & Gut Health

1

To evaluate Triphala on gut microbiota and bowel regularity

2017 50 participants 4 weeks 500 mg/day Triphala
Human Study RCT Double-Blind Placebo Positive

Study Type

Randomised, double-blind, placebo-controlled

Purpose

To evaluate Triphala on gut microbiota and bowel regularity

Dose

500 mg/day Triphala

Participants

50 healthy adults with constipation

Duration

4 weeks

Results

Significant improvements in bowel frequency (p<0.001) and stool consistency. Beneficial bacteria increased. Bifidobacterium and Lactobacillus levels elevated. Gut transit normalised.

How They Measured It

Stool frequency, Bristol stool scale, gut microbiome analysis

Read full study
2

To assess Triphala on functional constipation and IBS symptoms

2019 60 participants 8 weeks 500 mg/day Triphala
Human Study RCT Double-Blind Placebo Positive

Study Type

Randomised, double-blind, placebo-controlled

Purpose

To assess Triphala on functional constipation and IBS symptoms

Dose

500 mg/day Triphala

Participants

60 adults with functional constipation

Duration

8 weeks

Results

Significant increase in complete spontaneous bowel movements (p=0.001). IBS-QOL improved significantly. Abdominal discomfort and bloating reduced. Safe and well-tolerated.

How They Measured It

BSFS, IBS-QOL, complete bowel movement frequency

Read full study

Antioxidant & Anti-inflammatory

3

To evaluate Triphala on antioxidant status and inflammation

2014 50 participants 6 weeks 500 mg/day Triphala
Human Study RCT Double-Blind Placebo Positive

Study Type

Randomised, double-blind, placebo-controlled

Purpose

To evaluate Triphala on antioxidant status and inflammation

Dose

500 mg/day Triphala

Participants

50 healthy adults

Duration

6 weeks

Results

Significant increase in SOD and catalase enzyme activities. ORAC antioxidant capacity increased by 28%. CRP and IL-6 both reduced significantly vs placebo.

How They Measured It

ORAC, SOD, CAT, CRP, IL-6

Read full study
4

To assess Triphala on oxidative stress in patients with obesity

2018 45 participants 8 weeks 1000 mg/day Triphala
Human Study RCT Positive

Study Type

Randomised, controlled trial

Purpose

To assess Triphala on oxidative stress in patients with obesity

Dose

1000 mg/day Triphala

Participants

45 obese adults

Duration

8 weeks

Results

Significant reduction in MDA (p=0.02) and 8-OHdG oxidative markers. FRAP antioxidant capacity increased. Oxidative stress burden reduced despite no weight change.

How They Measured It

MDA, 8-OHdG, FRAP, antioxidant status

Read full study

Weight Management & Metabolic Health

5

To evaluate Triphala on weight management and metabolic markers in overweight adults

2012 75 participants 12 weeks 5 g/day Triphala powder
Human Study RCT Double-Blind Placebo Positive

Study Type

Randomised, double-blind, placebo-controlled

Purpose

To evaluate Triphala on weight management and metabolic markers in overweight adults

Dose

5 g/day Triphala powder

Participants

75 overweight adults

Duration

12 weeks

Results

Significant reduction in body weight (-2.2 kg), BMI, and waist circumference (p<0.05). Triglycerides and LDL reduced. Fasting glucose improved. Metabolic benefits demonstrated.

How They Measured It

Body weight, BMI, waist circumference, lipids, fasting glucose

Read full study
6

To assess Triphala on blood glucose and HbA1c in type 2 diabetes

2011 60 participants 45 days 5 g/day Triphala powder
Human Study RCT Double-Blind Placebo Positive

Study Type

Randomised, double-blind, placebo-controlled

Purpose

To assess Triphala on blood glucose and HbA1c in type 2 diabetes

Dose

5 g/day Triphala powder

Participants

60 type 2 diabetes patients

Duration

45 days

Results

Significant reduction in FPG (p<0.001) and HbA1c (-0.4%) vs placebo. Postprandial glucose also improved. Alpha-glucosidase inhibitory activity proposed as mechanism.

How They Measured It

FPG, HbA1c, HOMA-IR, postprandial glucose

Read full study

Oral Health

7

To evaluate Triphala mouthwash on dental caries and plaque

2005 60 participants 6 weeks Triphala mouthwash 10 ml twice daily
Human Study RCT Double-Blind Placebo Positive

Study Type

Randomised, double-blind, placebo-controlled

Purpose

To evaluate Triphala mouthwash on dental caries and plaque

Dose

Triphala mouthwash 10 ml twice daily

Participants

60 schoolchildren

Duration

6 weeks

Results

Significant reduction in plaque index (p<0.001) and gingival index. Caries-causing bacteria (S. mutans) reduced significantly. Comparable to chlorhexidine mouthwash. No staining side effect.

How They Measured It

Plaque index, gingival index, caries activity

Read full study
8

To assess Triphala on periodontal health in adults with gingivitis

2010 40 participants 4 weeks Triphala extract mouthwash twice daily
Human Study RCT Positive

Study Type

Randomised, controlled trial

Purpose

To assess Triphala on periodontal health in adults with gingivitis

Dose

Triphala extract mouthwash twice daily

Participants

40 adults with mild-moderate gingivitis

Duration

4 weeks

Results

Significant reduction in gingival inflammation and bleeding on probing. Plaque reduced. Periodontal improvement comparable to standard treatments. Good antimicrobial spectrum.

How They Measured It

GI, PI, bleeding on probing, pocket depth

Read full study

Cancer Prevention & Immunity

9

To evaluate Triphala on immune function markers in healthy adults

2016 30 participants 6 weeks 500 mg/day Triphala
Human Study RCT Positive

Study Type

Randomised, controlled pilot

Purpose

To evaluate Triphala on immune function markers in healthy adults

Dose

500 mg/day Triphala

Participants

30 healthy adults

Duration

6 weeks

Results

Significant improvement in NK cell activity (p=0.04) and lymphocyte proliferation. IL-2 production increased. Immunomodulatory effects confirmed. Anti-tumour potential suggested.

How They Measured It

NK cell activity, lymphocyte proliferation, IL-2, TNF-alpha

Read full study
10

To review clinical evidence for Triphala across health outcomes

2022 ? participants Various Various
Review/Other Mixed

Study Type

Systematic review

Purpose

To review clinical evidence for Triphala across health outcomes

Dose

Various

Participants

Systematic review

Duration

Various

Results

Strong evidence for digestive benefits. Good evidence for antioxidant, anti-inflammatory, and metabolic effects. Oral health benefits unique among herbal supplements. Overall excellent safety profile.

How They Measured It

Systematic review of clinical trials

Read full study

Frequently Asked Questions

Common questions about Triphala research

What does the research say about Triphala?

There are currently 10 peer-reviewed studies on Triphala (Triphala), involving 720 total participants. Research covers Digestive health, Antioxidant status, Anti-inflammatory and 2 more areas. The overall evidence strength is rated as Very Strong.

How strong is the evidence for Triphala?

The evidence is currently rated as "Very Strong Evidence". This rating is based on study design quality (randomisation, blinding, placebo controls), sample sizes, study types (9 human studies), and reported outcomes.

What health goals has Triphala been studied for?

Triphala has been researched for: Digestive health, Antioxidant status, Anti-inflammatory, Weight management, Oral health. Each area has its own body of evidence which you can explore in the study breakdowns above.

Are the studies on Triphala based on human trials?

Yes, 9 out of 10 studies are human trials. Human trials carry more weight in our evidence scoring system.