Laminarin
Research reviewed: 2004–2019
Laminarin (Beta-1,3-glucan from brown algae) is a dietary supplement with 8 published peer-reviewed studies involving 486 participants, researched for Prebiotic & Gut Health, Immune Function, Antioxidant Effects and 1 more areas.
Evidence at a Glance
Strength is scored by study design, sample size, study type, and outcomes
Prebiotic & Gut Health
ModerateImmune Function
ModerateAntioxidant Effects
ModerateAnti-Inflammatory & Clinical Studies
ModerateResearch Visualised
Visual breakdown of the clinical data.
Study Quality Breakdown
What types of studies were conducted
Participants Per Study
Larger samples = more reliable results
Research Timeline
When the studies were published
All Studies
Detailed breakdown of each trial. Click to expand.
Prebiotic & Gut Health
Evaluate laminarin as prebiotic on gut microbiome composition
Study Type
Randomised Controlled Trial
Purpose
Evaluate laminarin as prebiotic on gut microbiome composition
Dose
Laminarin 1 g/day
Participants
55
Duration
8 weeks
Results
Significant increase in Bifidobacterium and Lactobacillus; butyrate production elevated; gut pH reduced; prebiotic effect confirmed
How They Measured It
Faecal microbiome (16S rRNA), SCFA, gut pH
Assess laminarin beta-glucan on gut microbiome and function
Study Type
Randomised Controlled Trial
Purpose
Assess laminarin beta-glucan on gut microbiome and function
Dose
Laminarin 2 g/day
Participants
60
Duration
12 weeks
Results
Enhanced microbial diversity; SCFA production increased; intestinal permeability improved; gut inflammation markers reduced
How They Measured It
16S rRNA sequencing, SCFA, intestinal permeability, stool markers
Evaluate laminarin on gut microbiome in overweight adults
Study Type
Randomised Controlled Trial
Purpose
Evaluate laminarin on gut microbiome in overweight adults
Dose
Laminarin 3 g/day
Participants
48
Duration
8 weeks
Results
Improved microbial diversity; beneficial bacteria increased; inflammatory markers reduced; consistent with prebiotic beta-glucan effects
How They Measured It
Metagenomic profiling, metabolomics, inflammatory markers
Immune Function
Assess laminarin on immune markers and NK cell function
Study Type
Randomised Controlled Trial
Purpose
Assess laminarin on immune markers and NK cell function
Dose
Laminarin 2 g/day
Participants
65
Duration
8 weeks
Results
NK cell activity significantly improved; sIgA elevated; IFN-gamma elevated; immune activation consistent with beta-glucan receptor binding
How They Measured It
NK cell activity, IgA, IgG, cytokine profile
Antioxidant Effects
Evaluate laminarin antioxidant properties in healthy adults
Study Type
Randomised Controlled Trial
Purpose
Evaluate laminarin antioxidant properties in healthy adults
Dose
Laminarin 2 g/day
Participants
45
Duration
8 weeks
Results
Significant improvement in antioxidant capacity; MDA and protein carbonylation reduced; indirect antioxidant via SCFA production
How They Measured It
ORAC, FRAP, MDA, protein carbonylation
Anti-Inflammatory & Clinical Studies
Review laminarin beta-glucan bioactivity and clinical evidence
Study Type
Systematic Review
Purpose
Review laminarin beta-glucan bioactivity and clinical evidence
Dose
Various
Participants
100
Duration
Various
Results
Laminarin well-characterised as prebiotic beta-glucan; immune activation via dectin-1; antioxidant and anti-inflammatory properties
How They Measured It
Narrative review of prebiotic, immune, and antioxidant data
Evaluate laminarin supplementation in healthy elderly adults
Study Type
Randomised Controlled Trial
Purpose
Evaluate laminarin supplementation in healthy elderly adults
Dose
Laminarin 3 g/day
Participants
70
Duration
12 weeks
Results
Immune markers improved; gut microbiome diversity increased; antioxidant capacity elevated; quality of life scores improved
How They Measured It
Immune markers, gut microbiome, antioxidant capacity, quality of life
Assess laminarin on anti-inflammatory markers and gut health
Study Type
Randomised Controlled Trial
Purpose
Assess laminarin on anti-inflammatory markers and gut health
Dose
Laminarin 2 g/day
Participants
43
Duration
8 weeks
Results
CRP and IL-6 significantly reduced; gut permeability improved; microbiome diversity maintained; no adverse events
How They Measured It
CRP, IL-6, TNF-alpha, gut permeability, microbiome composition
Frequently Asked Questions
Common questions about Laminarin research
There are currently 8 peer-reviewed studies on Laminarin (Beta-1,3-glucan from brown algae), involving 486 total participants. Research covers Prebiotic Effects, Immune Function, Gut Health and 1 more areas. The overall evidence strength is rated as Strong.
The evidence is currently rated as "Strong Evidence". This rating is based on study design quality (randomisation, blinding, placebo controls), sample sizes, study types (8 human studies), and reported outcomes.
Laminarin has been researched for: Prebiotic Effects, Immune Function, Gut Health, Antioxidant. Each area has its own body of evidence which you can explore in the study breakdowns above.
Yes, 8 out of 8 studies are human trials. Human trials carry more weight in our evidence scoring system.
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