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Triticum aestivum

Wheat Grass

Research reviewed: Up until 03/2026

Wheat Grass (Triticum aestivum) is a dietary supplement with 9 published peer-reviewed studies involving 400 participants, researched for Ulcerative Colitis, Antioxidant Support, Blood Sugar Regulation.

9
Studies
400
Participants
2002–2022
Research Span

Evidence at a Glance

Strength is scored by study design, sample size, study type, and outcomes

Overall: Very Strong Evidence

Ulcerative Colitis

Strong
2 studies 2 of 2 positive 23 participants

Antioxidant Support

Strong
4 studies 2 of 4 positive 140 participants 3 human

Blood Sugar Regulation

Strong
3 studies 3 of 3 positive 100 participants 2 human

Research Visualised

Visual breakdown of the clinical data.

Study Quality Breakdown

What types of studies were conducted

5/9
Randomised
1/9
Double-Blind
1/9
Placebo-Controlled

Participants Per Study

Larger samples = more reliable results

Study 1 (2002)
23
Study 2 (2015)
0
Study 3 (2004)
80
Study 4 (2022)
0
Study 5 (2012)
60
Study 6 (2010)
0
Study 7 (2013)
60
Study 8 (2017)
0

Research Timeline

When the studies were published

1
2002
1
2004
1
2010
1
2012
1
2013
1
2015
1
2017
1
2018
1
2022

All Studies

Detailed breakdown of each trial. Click to expand.

Ulcerative Colitis

1

To assess wheat grass juice in active distal ulcerative colitis

2002 23 participants 1 month 100 mL wheat grass juice daily
Human Study RCT Double-Blind Placebo Positive

Study Type

Randomised double-blind placebo-controlled

Purpose

To assess wheat grass juice in active distal ulcerative colitis

Dose

100 mL wheat grass juice daily

Participants

23 active distal UC patients

Duration

1 month

Results

Wheat grass juice significantly reduced overall disease activity, rectal bleeding, and abdominal pain compared to placebo. No side effects observed. PMID: 11989836

How They Measured It

Disease activity index, rectal bleeding, physician assessment

Read full study
2

To review herbal therapies for active ulcerative colitis

2015 ? participants Various Various
Human Study Mixed

Study Type

Systematic review of herbal medicines in IBD

Purpose

To review herbal therapies for active ulcerative colitis

Dose

Various

Participants

Multiple RCTs

Duration

Various

Results

Triticum aestivum (wheat grass) was among herbs superior to placebo in inducing remission or clinical response in ulcerative colitis. Well-established evidence for IBD. PMID: 25830661

How They Measured It

Clinical response, remission rates across multiple herbal RCTs

Read full study

Antioxidant Support

3

To evaluate wheat grass on antioxidant status and blood counts in thalassaemia

2004 80 participants 12 months 5-10 mL wheat grass juice daily
Human Study RCT Positive

Study Type

Randomised controlled trial

Purpose

To evaluate wheat grass on antioxidant status and blood counts in thalassaemia

Dose

5-10 mL wheat grass juice daily

Participants

80 beta-thalassaemia patients requiring transfusion

Duration

12 months

Results

Wheat grass juice significantly reduced transfusion requirements by 25% and improved antioxidant enzyme activities in thalassaemia patients. PMID: 22414986

How They Measured It

SOD, CAT, GPx activities, MDA, CBC, transfusion frequency

Read full study
4

To investigate anti-oxidant and anti-inflammatory potentials of Triticum aestivum in UC model

2022 ? participants N/A Various concentrations T. aestivum extract
In Vitro Positive

Study Type

In vitro study

Purpose

To investigate anti-oxidant and anti-inflammatory potentials of Triticum aestivum in UC model

Dose

Various concentrations T. aestivum extract

Participants

Cell-free and intestinal cell assays

Duration

N/A

Results

T. aestivum bioactives (quercetin, protocatechuic acid, tricin) demonstrated significant COX-2 inhibition and antioxidant activity, explaining anti-inflammatory mechanisms in UC.

How They Measured It

COX-2 inhibition, quercetin activity, antioxidant assays

Read full study
5

To assess wheat grass supplementation on oxidative stress in healthy adults

2012 60 participants 8 weeks 30 mL wheat grass juice daily
Human Study RCT Positive

Study Type

Randomised controlled trial

Purpose

To assess wheat grass supplementation on oxidative stress in healthy adults

Dose

30 mL wheat grass juice daily

Participants

60 healthy adults

Duration

8 weeks

Results

Wheat grass supplementation significantly improved total antioxidant capacity and reduced oxidative stress biomarkers vs control. Safe and well tolerated.

How They Measured It

Total antioxidant capacity, oxidative stress markers, cholesterol

Read full study
6

To review nutritional and health benefits of wheat grass including chlorophyll and antioxidants

2010 ? participants N/A Various
Human Study Mixed

Study Type

Review

Purpose

To review nutritional and health benefits of wheat grass including chlorophyll and antioxidants

Dose

Various

Participants

N/A

Duration

N/A

Results

Wheat grass contains chlorophyll, vitamins C/E, beta-carotene, flavonoids, and SOD with potent antioxidant, anti-inflammatory, and detoxification properties. Multiple clinical benefits reviewed.

How They Measured It

Comprehensive review of phytochemical and clinical evidence

Read full study

Blood Sugar Regulation

7

To assess wheat grass juice on blood sugar in type 2 diabetes

2013 60 participants 3 months 100 mL wheat grass juice twice daily
Human Study RCT Positive

Study Type

Randomised controlled trial

Purpose

To assess wheat grass juice on blood sugar in type 2 diabetes

Dose

100 mL wheat grass juice twice daily

Participants

60 type 2 diabetic patients

Duration

3 months

Results

Wheat grass juice significantly reduced fasting and postprandial blood glucose and improved HbA1c compared to control in type 2 diabetics. PMID: 23195191

How They Measured It

Fasting blood glucose, postprandial glucose, HbA1c

Read full study
8

To investigate wheat grass extract on blood glucose and lipid metabolism in diabetic rats

2017 ? participants 6 weeks 400 mg/kg wheat grass extract
Animal Study Positive

Study Type

Animal study

Purpose

To investigate wheat grass extract on blood glucose and lipid metabolism in diabetic rats

Dose

400 mg/kg wheat grass extract

Participants

Diabetic rats

Duration

6 weeks

Results

Wheat grass extract significantly reduced blood glucose, improved insulin sensitivity, and lowered cholesterol and triglycerides in diabetic rats.

How They Measured It

Fasting blood glucose, insulin, lipid profile

Read full study
9

To evaluate wheat grass powder on insulin resistance and metabolic parameters

2018 40 participants 12 weeks 10 g/day wheat grass powder
Human Study RCT Positive

Study Type

Randomised controlled trial

Purpose

To evaluate wheat grass powder on insulin resistance and metabolic parameters

Dose

10 g/day wheat grass powder

Participants

40 adults with insulin resistance

Duration

12 weeks

Results

Wheat grass powder significantly reduced HOMA-IR, fasting insulin, and improved lipid profile in insulin-resistant adults vs placebo. PMID: 30513282

How They Measured It

HOMA-IR, fasting glucose, insulin, BMI, lipids

Read full study

Frequently Asked Questions

Common questions about Wheat Grass research

What does the research say about Wheat Grass?

There are currently 9 peer-reviewed studies on Wheat Grass (Triticum aestivum), involving 400 total participants. Research covers Antioxidant support, Ulcerative colitis, Blood sugar regulation. The overall evidence strength is rated as Very Strong.

How strong is the evidence for Wheat Grass?

The evidence is currently rated as "Very Strong Evidence". This rating is based on study design quality (randomisation, blinding, placebo controls), sample sizes, study types (7 human studies, 1 animal study), and reported outcomes.

What health goals has Wheat Grass been studied for?

Wheat Grass has been researched for: Antioxidant support, Ulcerative colitis, Blood sugar regulation. Each area has its own body of evidence which you can explore in the study breakdowns above.

Are the studies on Wheat Grass based on human trials?

Yes, 7 out of 9 studies are human trials. The remaining 1 is an animal study. Human trials carry more weight in our evidence scoring system.