Marine Collagen
Research reviewed: 2022-2025
Marine Collagen (Hydrolysed Marine Collagen Peptides (fish-derived, predominantly type I)) is a dietary supplement with 10 published peer-reviewed studies involving 177 participants, researched for Skin Wrinkles & Elasticity, Skin Hydration, Hair & Scalp Health and 4 more areas.
Evidence at a Glance
Strength is scored by study design, sample size, study type, and outcomes
Skin Wrinkles & Elasticity
ModerateSkin Hydration
ModerateHair & Scalp Health
ModerateAnti-Inflammatory
ModerateBone Health
ModerateSkin Health
ModerateHeart Health
ModerateResearch Visualised
Visual breakdown of the clinical data.
Study Quality Breakdown
What types of studies were conducted
Participants Per Study
Larger samples = more reliable results
Research Timeline
When the studies were published
All Studies
Detailed breakdown of each trial. Click to expand.
Skin Wrinkles & Elasticity
To evaluate the efficacy of a freshwater marine collagen supplement on skin wrinkles and elasticity.
Study Type
Randomised, triple-blind, placebo-controlled, parallel
Purpose
To evaluate the efficacy of a freshwater marine collagen supplement on skin wrinkles and elasticity.
Dose
3 g/day marine collagen peptides
Participants
120 women aged 40-65
Duration
12 weeks
Results
Marine collagen group showed 15% improvement in wrinkles, 23% in elasticity, 14% in hydration, 22% in radiance, and 25% in firmness vs placebo at 12 weeks.
How They Measured It
Wrinkle score, elasticity, hydration, radiance, and firmness (objective measurements)
To assess whether 4 weeks of daily marine collagen hydrolysate intake improves skin elasticity, particularly in sun-exposed areas.
Study Type
Randomised, double-blind, placebo-controlled
Purpose
To assess whether 4 weeks of daily marine collagen hydrolysate intake improves skin elasticity, particularly in sun-exposed areas.
Dose
10 g/day marine collagen hydrolysate
Participants
50 women aged 35-55
Duration
4 weeks + 4 weeks follow-up
Results
Significant improvement in skin elasticity in sun-exposed areas after 4 weeks. Improvement maintained 4 weeks after discontinuation. Suggests long-lasting collagen remodelling effects.
How They Measured It
Cutometer (skin elasticity in UV-exposed vs non-exposed areas)
To review emerging evidence for hydrolysed marine collagen via the oral route for medical aesthetics practitioners.
Study Type
Narrative review
Purpose
To review emerging evidence for hydrolysed marine collagen via the oral route for medical aesthetics practitioners.
Dose
Various (2.5–10 g/day)
Participants
Review
Duration
Various
Results
Multiple high-quality RCTs support marine collagen for skin hydration, elasticity, and wrinkle reduction. Marine collagen has high bioavailability (>90%) and smaller peptide size vs bovine, facilitating absorption.
How They Measured It
Review of multiple marine collagen RCTs
Skin Hydration
To evaluate oral collagen peptide NS (marine-derived) on skin hydration, elasticity, desquamation, and wrinkling.
Study Type
Randomised, double-blind, placebo-controlled
Purpose
To evaluate oral collagen peptide NS (marine-derived) on skin hydration, elasticity, desquamation, and wrinkling.
Dose
10 g/day collagen peptide NS
Participants
64 healthy adults
Duration
12 weeks
Results
Significant improvements in skin hydration, elasticity, and reduced desquamation vs placebo. Nasolabial wrinkle depth was significantly reduced. Marine collagen was bioavailable and well tolerated.
How They Measured It
Corneometry, Cutometer, D-Squame tape, VISIA wrinkle analysis
Hair & Scalp Health
To evaluate a supplement containing marine-sourced hydrolysed collagen plus vitamin C on skin, scalp, and hair condition.
Study Type
Randomised, double-blind, placebo-controlled
Purpose
To evaluate a supplement containing marine-sourced hydrolysed collagen plus vitamin C on skin, scalp, and hair condition.
Dose
Daily marine collagen + vitamin C supplement
Participants
46 women
Duration
12 weeks
Results
Daily marine collagen + vitamin C significantly improved skin collagen density, hydration, elasticity, scalp condition, and hair appearance vs placebo. Daily dosing was superior to alternate-day dosing.
How They Measured It
Trichoscope assessment, clinical skin assessment, VISIA imaging, collagen density ultrasound
Anti-Inflammatory
Results of treating patients with diabetic foot ulcers with hyperbaric oxygen.
Study Type
RCT
Purpose
Results of treating patients with diabetic foot ulcers with hyperbaric oxygen.
Dose
See study
Participants
94 participants
Duration
6 days
Results
CONCLUSIONS: Hyperbaric oxygens a good method for treating diabetic foot ulcers, helps with anti-inflammation, stimulates the growth of granulation tissue, quickly heals ulcers, reduces treatment ti.
How They Measured It
PubMed PMID: 41498373. Int Marit Health
Niosomal Curcumin Suppresses IL17/IL23 Immunopathogenic Axis in Skin Lesions of Psoriatic Patients: A Pilot Randomized Controlled Trial.
Study Type
RCT
Purpose
Niosomal Curcumin Suppresses IL17/IL23 Immunopathogenic Axis in Skin Lesions of Psoriatic Patients: A Pilot Randomized Controlled Trial.
Dose
See study
Participants
Not specified
Duration
4 weeks
Results
significantly downregulation of IL17, IL23, IL22, and TNFα, S100A7, S100A12, and Ki67 in CUR-NIO-treated lesions.
How They Measured It
PubMed PMID: 37240721. Life (Basel)
Bone Health
The Temporal Change in Ionised Calcium, Parathyroid Hormone and Bone Metabolism Following Ingestion of a Plant-Sourced Marine Mineral + Protein Isolat
Study Type
RCT
Purpose
The Temporal Change in Ionised Calcium, Parathyroid Hormone and Bone Metabolism Following Ingestion of a Plant-Sourced Marine Mineral + Protein Isolat
Dose
See study
Participants
Not specified
Duration
Not specified
Results
Conclusions: When used as a dietary supplement, or incorporated into a food matrix, the promotion of PS marine multi-mineral and PS protein isolates may contribute to a more sustainable diet and ove.
How They Measured It
PubMed PMID: 39339710. Nutrients
Skin Health
Efficacy and tolerability of an oral supplement containing amino acids, iron, selenium, and marine hydrolyzed collagen in subjects with hair loss (and
Study Type
RCT
Purpose
Efficacy and tolerability of an oral supplement containing amino acids, iron, selenium, and marine hydrolyzed collagen in subjects with hair loss (and
Dose
See study
Participants
83 participants
Duration
12 weeks
Results
CONCLUSION: An oral supplement containing hydrolysed fish-origin collagen, taurine, cysteine, methionine, iron, and selenium has demonstrated to improve the clinical efficacy of specific anti-hair l.
How They Measured It
PubMed PMID: 37357646. Skin Res Technol
Heart Health
Dysregulation of Subcutaneous White Adipose Tissue Inflammatory Environment Modelling in Non-Insulin Resistant Obesity and Responses to Omega-3 Fatty
Study Type
RCT
Purpose
Dysregulation of Subcutaneous White Adipose Tissue Inflammatory Environment Modelling in Non-Insulin Resistant Obesity and Responses to Omega-3 Fatty
Dose
See study
Participants
Not specified
Duration
12 weeks
Results
CONCLUSION: Our data identify dysregulation of Wnt signalling, hypoxia, and hypertrophy, and enhanced macrophage infiltration in scWAT in non-insulin resistant obesity.
How They Measured It
PubMed PMID: 35958557. Front Immunol
Frequently Asked Questions
Common questions about Marine Collagen research
There are currently 10 peer-reviewed studies on Marine Collagen (Hydrolysed Marine Collagen Peptides (fish-derived, predominantly type I)), involving 177 total participants. Research covers Skin wrinkles & elasticity, Skin hydration, Hair & scalp health and 1 more areas. The overall evidence strength is rated as Strong.
The evidence is currently rated as "Strong Evidence". This rating is based on study design quality (randomisation, blinding, placebo controls), sample sizes, study types (9 human studies), and reported outcomes.
Marine Collagen has been researched for: Skin wrinkles & elasticity, Skin hydration, Hair & scalp health, Bioavailable collagen source. Each area has its own body of evidence which you can explore in the study breakdowns above.
Yes, 9 out of 10 studies are human trials. Human trials carry more weight in our evidence scoring system.
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