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Althaea officinalis

Marshmallow Root

Research reviewed: Up until 03/2026

Marshmallow Root (Althaea officinalis) is a dietary supplement with 8 published peer-reviewed studies involving 320 participants, researched for Respiratory Health, GI Mucosa Support, Anti-Inflammatory.

8
Studies
320
Participants
2003–2021
Research Span

Evidence at a Glance

Strength is scored by study design, sample size, study type, and outcomes

Overall: Moderate Evidence

Respiratory Health

Moderate
3 studies 1 of 3 positive 1,422 participants 1 human

GI Mucosa Support

Moderate
2 studies 1 of 2 positive 31 participants 1 human

Anti-Inflammatory

Weak
3 studies 1 of 3 positive 0 participants 0 human

Research Visualised

Visual breakdown of the clinical data.

Study Quality Breakdown

What types of studies were conducted

1/8
Randomised
0/8
Double-Blind
0/8
Placebo-Controlled

Participants Per Study

Larger samples = more reliable results

Study 1 (2018)
1,422
Study 2 (2019)
0
Study 3 (2020)
0
Study 4 (2011)
31
Study 5 (2014)
0
Study 6 (2003)
0
Study 7 (2015)
0
Study 8 (2021)
0

Research Timeline

When the studies were published

1
2003
1
2011
1
2014
1
2015
1
2018
1
2019
1
2020
1
2021

All Studies

Detailed breakdown of each trial. Click to expand.

Respiratory Health

1

To evaluate marshmallow root extract for symptomatic treatment of irritative dry cough

2018 1422 participants 2 surveys over several weeks Marshmallow root syrup or tablets
Human Study Mixed

Study Type

Observational survey study

Purpose

To evaluate marshmallow root extract for symptomatic treatment of irritative dry cough

Dose

Marshmallow root syrup or tablets

Participants

Multi-centre: 1422 patients total

Duration

2 surveys over several weeks

Results

Both marshmallow preparations effectively reduced dry cough symptoms. Syrup superior to tablets for immediate relief. Results justify long-established use. PMID: 30064132

How They Measured It

Cough severity, frequency, patient satisfaction

Read full study
2

To review Althaea officinalis potency in treatment of cough and respiratory conditions

2019 ? participants N/A Various
Review/Other Mixed

Study Type

Review

Purpose

To review Althaea officinalis potency in treatment of cough and respiratory conditions

Dose

Various

Participants

N/A

Duration

N/A

Results

Marshmallow root (A. officinalis) contains mucilaginous polysaccharides forming protective film on irritated mucosa, reducing cough and sore throat irritation. Combined preparations more effective. PMID: 31770755

How They Measured It

Systematic review of phytotherapeutic evidence

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3

To assess anti-inflammatory and anti-oxidative effects of marshmallow on macrophages

2020 ? participants N/A Various concentrations Phytohustil® and root extract
In Vitro Positive

Study Type

In vitro study

Purpose

To assess anti-inflammatory and anti-oxidative effects of marshmallow on macrophages

Dose

Various concentrations Phytohustil® and root extract

Participants

LPS-activated macrophage cultures

Duration

N/A

Results

Marshmallow root extract significantly reduced inflammatory cytokine release and oxidative stress in macrophages via NF-kB inhibition. Anti-inflammatory mechanism confirmed. PMCID: PMC7090173

How They Measured It

NF-kB, cytokine release, ROS production in LPS-activated macrophages

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GI Mucosa Support

4

To evaluate slippery elm and marshmallow root combination on IBS symptoms

2011 31 participants 4 weeks Slippery elm bark + marshmallow root combination
Human Study RCT Positive

Study Type

Randomised controlled trial (multi-ingredient)

Purpose

To evaluate slippery elm and marshmallow root combination on IBS symptoms

Dose

Slippery elm bark + marshmallow root combination

Participants

31 IBS patients

Duration

4 weeks

Results

Marshmallow-containing formula significantly reduced IBS symptoms and improved bowel consistency and frequency in constipation-predominant IBS. PMID: 20954962

How They Measured It

IBS symptom score, bowel habit

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5

To investigate marshmallow root mucilage gastroprotective properties

2014 ? participants 7 days 250-1000 mg/kg extract
Animal Study Mixed

Study Type

Animal study

Purpose

To investigate marshmallow root mucilage gastroprotective properties

Dose

250-1000 mg/kg extract

Participants

Rats with gastric ulcers

Duration

7 days

Results

Marshmallow root extract dose-dependently reduced ulcer area and increased gastric mucus secretion and prostaglandin E2, confirming gastroprotective mechanism.

How They Measured It

Gastric ulcer area, mucus secretion, prostaglandin levels

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Anti-Inflammatory

6

To evaluate marshmallow polysaccharides on complement system and inflammation

2003 ? participants N/A Various concentrations
In Vitro Positive

Study Type

In vitro study

Purpose

To evaluate marshmallow polysaccharides on complement system and inflammation

Dose

Various concentrations

Participants

Human blood and cell cultures

Duration

N/A

Results

Marshmallow polysaccharides demonstrated significant complement-modulating and anti-inflammatory activity, reducing excessive immune activation relevant to allergic and inflammatory conditions.

How They Measured It

Complement activation, ELISA for inflammatory markers

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7

To assess marshmallow root anti-inflammatory effects in paw oedema model

2015 ? participants 6 hours 200-400 mg/kg extract
Animal Study Positive

Study Type

Animal study

Purpose

To assess marshmallow root anti-inflammatory effects in paw oedema model

Dose

200-400 mg/kg extract

Participants

Rats

Duration

6 hours

Results

Marshmallow root extract significantly reduced carrageenan-induced paw oedema in a dose-dependent manner, confirming systemic anti-inflammatory effects.

How They Measured It

Paw oedema volume, inflammatory cytokines

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8

To review herbal medicines containing mucilage for inflammatory conditions

2021 ? participants N/A Various
Review/Other Mixed

Study Type

Systematic review

Purpose

To review herbal medicines containing mucilage for inflammatory conditions

Dose

Various

Participants

N/A

Duration

N/A

Results

Mucilaginous herbs including marshmallow demonstrate protective, anti-inflammatory, and soothing effects on irritated mucosal surfaces across multiple body systems. Strong safety profile established.

How They Measured It

Evidence synthesis across multiple mucilaginous herbs

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Frequently Asked Questions

Common questions about Marshmallow Root research

What does the research say about Marshmallow Root?

There are currently 8 peer-reviewed studies on Marshmallow Root (Althaea officinalis), involving 320 total participants. Research covers Respiratory health, GI mucosa support, Anti-inflammatory. The overall evidence strength is rated as Moderate.

How strong is the evidence for Marshmallow Root?

The evidence is currently rated as "Moderate Evidence". This rating is based on study design quality (randomisation, blinding, placebo controls), sample sizes, study types (2 human studies, 2 animal studies), and reported outcomes.

What health goals has Marshmallow Root been studied for?

Marshmallow Root has been researched for: Respiratory health, GI mucosa support, Anti-inflammatory. Each area has its own body of evidence which you can explore in the study breakdowns above.

Are the studies on Marshmallow Root based on human trials?

Yes, 2 out of 8 studies are human trials. The remaining 2 are animal studies. Human trials carry more weight in our evidence scoring system.