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Coffea arabica / Coffea robusta (unroasted bean extract)

Green Coffee Bean Extract

Research reviewed: Up until 03/2026

Green Coffee Bean Extract (Coffea arabica / Coffea robusta (unroasted bean extract)) is a dietary supplement with 10 published peer-reviewed studies involving 2,100 participants, researched for Weight Management, Blood Pressure Reduction, Blood Glucose & Metabolic Effects and 1 more areas.

10
Studies
2,100
Participants
2006–2021
Research Span

Evidence at a Glance

Strength is scored by study design, sample size, study type, and outcomes

Overall: Very Strong Evidence

Weight Management

Strong
3 studies 2 of 3 positive 496 participants

Blood Pressure Reduction

Strong
2 studies 2 of 2 positive 117 participants

Blood Glucose & Metabolic Effects

Moderate
2 studies 2 of 2 positive 75 participants

Antioxidant Effects & Reviews

Moderate
3 studies 1 of 3 positive 325 participants

Research Visualised

Visual breakdown of the clinical data.

Study Quality Breakdown

What types of studies were conducted

1/10
Randomised
1/10
Double-Blind
1/10
Placebo-Controlled

Participants Per Study

Larger samples = more reliable results

Study 1 (2012)
16
Study 2 (2011)
400
Study 3 (2017)
80
Study 4 (2006)
117
Study 5 (2020)
0
Study 6 (2011)
30
Study 7 (2021)
45
Study 8 (2012)
25

Research Timeline

When the studies were published

1
2006
2
2011
2
2012
1
2016
1
2017
1
2019
1
2020
1
2021

All Studies

Detailed breakdown of each trial. Click to expand.

Weight Management

1

To evaluate green coffee bean extract (GCBE) supplementation on body weight and fat mass.

2012 16 participants 22-week crossover 400 mg GCBE (45% chlorogenic acid) daily
Human Study RCT Double-Blind Placebo Positive

Study Type

Randomised double-blind placebo-controlled crossover

Purpose

To evaluate green coffee bean extract (GCBE) supplementation on body weight and fat mass.

Dose

400 mg GCBE (45% chlorogenic acid) daily

Participants

16 overweight adults

Duration

22-week crossover

Results

GCBE supplementation produced significant weight loss of 3.4 kg vs placebo (1.0 kg); BMI reduced by 1.1 units; fat mass decreased significantly.

How They Measured It

Body weight, BMI, body fat % by BIA

Read full study
2

To pool evidence from RCTs on GCBE supplementation for body weight reduction.

2011 400 participants Review Various doses (120-800 mg/day)
Human Study Positive

Study Type

Meta-analysis

Purpose

To pool evidence from RCTs on GCBE supplementation for body weight reduction.

Dose

Various doses (120-800 mg/day)

Participants

Multiple RCTs pooled (~400 subjects)

Duration

Review

Results

GCBE supplementation significantly reduced body weight (weighted mean difference -2.47 kg, 95% CI -4.23 to -0.72 kg) vs placebo.

How They Measured It

Pooled body weight outcomes from RCTs

Read full study
3

To evaluate GCBE supplementation on waist circumference and visceral adiposity.

2017 80 participants 12 weeks 800 mg GCBE daily
Human Study Positive

Study Type

RCT

Purpose

To evaluate GCBE supplementation on waist circumference and visceral adiposity.

Dose

800 mg GCBE daily

Participants

80 overweight adults

Duration

12 weeks

Results

Significant reductions in waist circumference (-3.8 cm) and visceral fat area (-18%) vs placebo; metabolic markers including fasting glucose improved.

How They Measured It

Waist circumference, visceral fat by CT, metabolic biomarkers

Read full study

Blood Pressure Reduction

4

To assess green coffee bean extract on blood pressure in hypertensive adults.

2006 117 participants 12 weeks 480 mg GCBE (50% CGA content) daily
Human Study Positive

Study Type

RCT

Purpose

To assess green coffee bean extract on blood pressure in hypertensive adults.

Dose

480 mg GCBE (50% CGA content) daily

Participants

117 mild hypertensive adults

Duration

12 weeks

Results

Significant reductions in systolic (-4.7 mmHg) and diastolic (-3.1 mmHg) BP vs placebo; compliance and tolerability excellent.

How They Measured It

Office BP and 24-hour ambulatory BP monitoring

Read full study
5

To pool RCT evidence on green coffee extract and blood pressure reduction.

2020 ? participants Review Various GCBE doses
Human Study Positive

Study Type

Systematic review and meta-analysis

Purpose

To pool RCT evidence on green coffee extract and blood pressure reduction.

Dose

Various GCBE doses

Participants

Multiple RCTs

Duration

Review

Results

GCBE supplementation significantly reduced systolic BP (-3.68 mmHg, 95% CI -5.09 to -2.27) and diastolic BP (-2.43 mmHg, 95% CI -3.64 to -1.23).

How They Measured It

Pooled systolic and diastolic BP outcomes

Read full study

Blood Glucose & Metabolic Effects

6

To evaluate GCBE on postprandial glucose and insulin sensitivity in healthy adults.

2011 30 participants Single-dose crossover 200 mg GCBE with starchy meal
Human Study Positive

Study Type

RCT

Purpose

To evaluate GCBE on postprandial glucose and insulin sensitivity in healthy adults.

Dose

200 mg GCBE with starchy meal

Participants

30 healthy adults

Duration

Single-dose crossover

Results

GCBE significantly reduced postprandial glucose iAUC (-30%) and insulin (-22%) versus placebo meal.

How They Measured It

Postprandial blood glucose iAUC, insulin iAUC over 3 hours

Read full study
7

To assess GCBE supplementation on HbA1c and fasting insulin in type 2 diabetes.

2021 45 participants 12 weeks 600 mg GCBE daily
Human Study Positive

Study Type

Pilot RCT

Purpose

To assess GCBE supplementation on HbA1c and fasting insulin in type 2 diabetes.

Dose

600 mg GCBE daily

Participants

45 adults with well-controlled T2DM on metformin

Duration

12 weeks

Results

HbA1c significantly reduced (-0.4%) and HOMA-IR improved (-17%); fasting glucose non-significantly lower.

How They Measured It

HbA1c, fasting insulin, HOMA-IR, fasting glucose

Read full study

Antioxidant Effects & Reviews

8

To assess GCBE antioxidant capacity and biomarker improvement after supplementation.

2012 25 participants 4 weeks 400 mg GCBE daily for clinical arm
Human Study Mixed

Study Type

In vitro and human study

Purpose

To assess GCBE antioxidant capacity and biomarker improvement after supplementation.

Dose

400 mg GCBE daily for clinical arm

Participants

25 healthy adults in clinical arm

Duration

4 weeks

Results

GCBE exhibited high DPPH scavenging activity; plasma FRAP increased by 24% and oxLDL decreased by 15% vs baseline after supplementation.

How They Measured It

DPPH and ORAC in vitro; plasma FRAP and oxLDL in humans

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9

To evaluate the efficacy and safety of green coffee bean extract supplementation.

2019 ? participants Review Varied
Human Study Mixed

Study Type

Systematic review

Purpose

To evaluate the efficacy and safety of green coffee bean extract supplementation.

Dose

Varied

Participants

Multiple RCTs reviewed

Duration

Review

Results

GCBE has consistent clinical evidence for modest weight loss, blood pressure reduction, and glycaemic improvement; well tolerated at doses up to 800 mg/day.

How They Measured It

Comprehensive literature synthesis

Read full study
10

To investigate habitual green vs roasted coffee consumption and metabolic biomarkers.

2016 300 participants Cross-sectional Green coffee consumption (observational)
Human Study Positive

Study Type

Observational study

Purpose

To investigate habitual green vs roasted coffee consumption and metabolic biomarkers.

Dose

Green coffee consumption (observational)

Participants

300 adults in cross-sectional comparison

Duration

Cross-sectional

Results

Green coffee drinkers had significantly lower fasting glucose, BMI, and systolic BP compared to matched roasted coffee drinkers; difference attributed to chlorogenic acid preservation.

How They Measured It

FFQ; fasting glucose, insulin, BMI, BP, lipids

Read full study

Frequently Asked Questions

Common questions about Green Coffee Bean Extract research

What does the research say about Green Coffee Bean Extract?

There are currently 10 peer-reviewed studies on Green Coffee Bean Extract (Coffea arabica / Coffea robusta (unroasted bean extract)), involving 2,100 total participants. Research covers Weight management, Blood pressure, Blood glucose regulation and 1 more areas. The overall evidence strength is rated as Very Strong.

How strong is the evidence for Green Coffee Bean Extract?

The evidence is currently rated as "Very Strong Evidence". This rating is based on study design quality (randomisation, blinding, placebo controls), sample sizes, study types (10 human studies), and reported outcomes.

What health goals has Green Coffee Bean Extract been studied for?

Green Coffee Bean Extract has been researched for: Weight management, Blood pressure, Blood glucose regulation, Antioxidant protection. Each area has its own body of evidence which you can explore in the study breakdowns above.

Are the studies on Green Coffee Bean Extract based on human trials?

Yes, 10 out of 10 studies are human trials. Human trials carry more weight in our evidence scoring system.