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Zingiber officinale (Ginger Root)

Ginger Extract

Research reviewed: Up until 03/2026

Ginger Extract (Zingiber officinale (Ginger Root)) is a dietary supplement with 9 published peer-reviewed studies involving 2,140 participants, researched for Blood Pressure & Cholesterol, Anti-inflammatory & Metabolic Effects.

9
Studies
2,140
Participants
2015–2025
Research Span

Evidence at a Glance

Strength is scored by study design, sample size, study type, and outcomes

Overall: Strong Evidence

Blood Pressure & Cholesterol

Moderate
4 studies 3 of 4 positive 3,110 participants 1 human

Anti-inflammatory & Metabolic Effects

Strong
5 studies 5 of 5 positive 287 participants 4 human

Research Visualised

Visual breakdown of the clinical data.

Study Quality Breakdown

What types of studies were conducted

6/9
Randomised
5/9
Double-Blind
4/9
Placebo-Controlled

Participants Per Study

Larger samples = more reliable results

Study 1 (2025)
2,025
Study 2 (2023)
1,000
Study 3 (2022)
0
Study 4 (2016)
85
Study 1 (2015)
88
Study 2 (2019)
75
Study 3 (2020)
60
Study 4 (2019)
0

Research Timeline

When the studies were published

1
2015
2
2016
2
2019
1
2020
1
2022
1
2023
1
2025

All Studies

Detailed breakdown of each trial. Click to expand.

Blood Pressure & Cholesterol

1

To evaluate ginger (Zingiber officinale) supplementation on biomarkers of cardiovascular disease.

2025 2025 participants 4–16 weeks Various ginger doses (0.5–5 g/day)
Review/Other RCT Positive

Study Type

Systematic review of randomised controlled trials

Purpose

To evaluate ginger (Zingiber officinale) supplementation on biomarkers of cardiovascular disease.

Dose

Various ginger doses (0.5–5 g/day)

Participants

Multiple RCTs (published up to January 2025)

Duration

4–16 weeks

Results

Ginger supplementation significantly reduced SBP, TC, LDL-C, and TG in pooled analyses. CRP and fasting glucose were also improved in subgroups. Effect sizes were moderate and consistent across different ginger formulations (powder, extract, fresh).

How They Measured It

Pooled blood pressure, lipid panel, CRP, fasting glucose from RCTs

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2

To meta-analyse the effect of ginger supplementation on lipid profile in humans.

2023 1,000 participants 4–12 weeks Various ginger doses and forms
Review/Other Positive

Study Type

Systematic review and meta-analysis

Purpose

To meta-analyse the effect of ginger supplementation on lipid profile in humans.

Dose

Various ginger doses and forms

Participants

Multiple RCTs (>1,000 participants)

Duration

4–12 weeks

Results

Ginger significantly reduced TC (WMD −9.4 mg/dL), TG (WMD −12.6 mg/dL), and LDL-C. HDL-C showed a non-significant trend toward improvement. Subgroup analysis showed stronger effects in diabetic patients and at doses ≥2 g/day.

How They Measured It

Pooled TC, LDL-C, HDL-C, TG from eligible RCTs (2010–2022)

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3

To analyse the effect of Zingiber officinale on dyslipidaemia, blood pressure, and inflammation as cardiovascular risk factors.

2022 ? participants 4–16 weeks Various (predominantly 1–3 g/day ginger powder)
Review/Other Mixed

Study Type

Systematic review

Purpose

To analyse the effect of Zingiber officinale on dyslipidaemia, blood pressure, and inflammation as cardiovascular risk factors.

Dose

Various (predominantly 1–3 g/day ginger powder)

Participants

Multiple clinical trials reviewed

Duration

4–16 weeks

Results

Evidence supports a beneficial effect of Zingiber officinale on dyslipidaemia and inflammation. Blood pressure effects were inconsistent but generally trending toward reduction. The review identified gaps in high-quality evidence and recommended further rigorous RCTs.

How They Measured It

Synthesis of lipid endpoints, SBP, DBP, and inflammatory markers from eligible clinical trials

Read full study
4

To assess ginger powder supplementation on blood pressure and lipid profile in patients with coronary artery disease.

2016 85 participants 8 weeks 4 g/day ginger powder
Human Study RCT Double-Blind Placebo Positive

Study Type

Randomised, double-blind, placebo-controlled

Purpose

To assess ginger powder supplementation on blood pressure and lipid profile in patients with coronary artery disease.

Dose

4 g/day ginger powder

Participants

85 patients with coronary artery disease

Duration

8 weeks

Results

Ginger powder significantly reduced TC (−12%), LDL-C (−14%), TG (−18%) and blood pressure compared to placebo. HDL-C improved marginally. Platelet aggregation was also reduced. Results support ginger as a complementary supplement in coronary artery disease.

How They Measured It

SBP, DBP, TC, LDL-C, HDL-C, TG at 4 and 8 weeks

Read full study

Anti-inflammatory & Metabolic Effects

1

To evaluate ginger supplementation on inflammatory and metabolic markers in type 2 diabetes.

2015 88 participants 12 weeks 2 g/day ginger powder
Human Study RCT Double-Blind Placebo Positive

Study Type

Randomised, double-blind, placebo-controlled

Purpose

To evaluate ginger supplementation on inflammatory and metabolic markers in type 2 diabetes.

Dose

2 g/day ginger powder

Participants

88 patients with type 2 diabetes

Duration

12 weeks

Results

Ginger significantly reduced CRP (−30%), TNF-alpha (−24%), and IL-6. HbA1c and fasting glucose improved significantly. Insulin resistance (HOMA-IR) was meaningfully reduced. The combined anti-inflammatory and glycaemic benefits support ginger for cardiovascular risk reduction in diabetes.

How They Measured It

CRP, IL-6, TNF-alpha, HbA1c, fasting glucose, insulin resistance

Read full study
2

To assess ginger capsules vs placebo on blood pressure in hypertensive patients.

2019 75 participants 8 weeks 3 g/day ginger capsules
Human Study RCT Double-Blind Positive

Study Type

Randomised, double-blind, controlled

Purpose

To assess ginger capsules vs placebo on blood pressure in hypertensive patients.

Dose

3 g/day ginger capsules

Participants

75 hypertensive adults

Duration

8 weeks

Results

Ginger supplementation produced significant reductions in SBP (−6.4 mmHg) and DBP (−3.9 mmHg) compared to placebo (p=0.02). Proposed mechanism includes calcium channel antagonism and ACE inhibition by gingerols and shogaols.

How They Measured It

Clinic SBP and DBP, 24-h ambulatory blood pressure

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3

To investigate the effect of ginger extract on oxidative stress and endothelial function markers in obese adults.

2020 60 participants 12 weeks 1,600 mg/day ginger extract
Human Study RCT Double-Blind Placebo Positive

Study Type

Randomised, double-blind, placebo-controlled

Purpose

To investigate the effect of ginger extract on oxidative stress and endothelial function markers in obese adults.

Dose

1,600 mg/day ginger extract

Participants

60 obese adults with cardiovascular risk factors

Duration

12 weeks

Results

Ginger extract significantly reduced MDA (oxidative stress marker) and improved FMD (endothelial function). TC and LDL-C were reduced. ICAM-1 (inflammation marker) was significantly lower vs placebo. Results support ginger for endothelial protection in obese cardiovascular risk patients.

How They Measured It

MDA, SOD, FMD, ICAM-1, blood pressure, lipid panel

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4

To evaluate ginger supplementation on blood pressure specifically across controlled clinical trials.

2019 ? participants 4–16 weeks Various (0.5–5 g/day)
Review/Other Positive

Study Type

Systematic review and meta-analysis

Purpose

To evaluate ginger supplementation on blood pressure specifically across controlled clinical trials.

Dose

Various (0.5–5 g/day)

Participants

Multiple RCTs pooled

Duration

4–16 weeks

Results

Ginger significantly reduced SBP (WMD −6.36 mmHg) and DBP (WMD −2.12 mmHg) overall. Effects were dose-dependent and stronger in hypertensive subjects and at treatment durations ≥8 weeks. Ginger is a promising adjunct for blood pressure management.

How They Measured It

Pooled SBP and DBP changes, subgroup analysis by dose, duration, and hypertension status

Read full study
5

To evaluate ginger on lipid profile in patients with non-alcoholic fatty liver disease (NAFLD).

2016 64 participants 12 weeks 2 g/day ginger powder
Human Study RCT Double-Blind Placebo Positive

Study Type

Randomised, double-blind, placebo-controlled

Purpose

To evaluate ginger on lipid profile in patients with non-alcoholic fatty liver disease (NAFLD).

Dose

2 g/day ginger powder

Participants

64 adults with NAFLD

Duration

12 weeks

Results

Ginger significantly reduced TC (−12%), TG (−16%), and LDL-C (−10%) vs placebo. Liver enzymes (ALT, AST) and hepatic steatosis on ultrasound also improved. The lipid-lowering effects in NAFLD are particularly relevant given the high cardiovascular risk in this population.

How They Measured It

TC, LDL-C, HDL-C, TG, liver ultrasound, liver enzymes

Read full study

Frequently Asked Questions

Common questions about Ginger Extract research

What does the research say about Ginger Extract?

There are currently 9 peer-reviewed studies on Ginger Extract (Zingiber officinale (Ginger Root)), involving 2,140 total participants. Research covers Blood pressure management, Cholesterol reduction, Anti-inflammatory cardiovascular effects and 1 more areas. The overall evidence strength is rated as Strong.

How strong is the evidence for Ginger Extract?

The evidence is currently rated as "Strong Evidence". This rating is based on study design quality (randomisation, blinding, placebo controls), sample sizes, study types (5 human studies), and reported outcomes.

What health goals has Ginger Extract been studied for?

Ginger Extract has been researched for: Blood pressure management, Cholesterol reduction, Anti-inflammatory cardiovascular effects, Triglyceride lowering. Each area has its own body of evidence which you can explore in the study breakdowns above.

Are the studies on Ginger Extract based on human trials?

Yes, 5 out of 9 studies are human trials. Human trials carry more weight in our evidence scoring system.