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Brown algae (Phaeophyceae) extract

Brown Seaweed Extract

Research reviewed: 2005–2018

Brown Seaweed Extract (Brown algae (Phaeophyceae) extract) is a dietary supplement with 9 published peer-reviewed studies involving 622 participants, researched for Metabolism, Antioxidant Effects, Anti-Inflammatory Effects and 1 more areas.

9
Studies
622
Participants
2005–2025
Research Span

Evidence at a Glance

Strength is scored by study design, sample size, study type, and outcomes

Overall: Strong Evidence

Metabolism

Moderate
3 studies 2 of 3 positive 148 participants 2 human

Antioxidant Effects

Strong
2 studies 2 of 2 positive 135 participants

Anti-Inflammatory Effects

Moderate
1 study 1 of 1 positive 65 participants

Thyroid Support & Clinical Evidence

Moderate
3 studies 1 of 3 positive 274 participants

Research Visualised

Visual breakdown of the clinical data.

Study Quality Breakdown

What types of studies were conducted

7/9
Randomised
0/9
Double-Blind
0/9
Placebo-Controlled

Participants Per Study

Larger samples = more reliable results

Study 1 (2005)
80
Study 2 (2013)
68
Study 9 (2025)
0
Study 3 (2012)
60
Study 4 (2015)
75
Study 5 (2008)
65
Study 6 (2017)
140
Study 7 (2018)
88

Research Timeline

When the studies were published

1
2005
1
2008
1
2012
1
2013
1
2015
1
2017
2
2018
1
2025

All Studies

Detailed breakdown of each trial. Click to expand.

Metabolism

1

Evaluate brown seaweed extract on metabolic rate and body composition

2005 80 participants 12 weeks Brown algae extract 3 g/day
Human Study RCT Mixed

Study Type

Randomised Controlled Trial

Purpose

Evaluate brown seaweed extract on metabolic rate and body composition

Dose

Brown algae extract 3 g/day

Participants

80

Duration

12 weeks

Results

RMR increased by 3.8% vs baseline; fat mass reduced (−0.9 kg); thyroid hormones elevated; iodine and fucoxanthin mechanisms

How They Measured It

RMR, body weight, fat mass, thyroid hormones

Read full study
2

Assess brown algae thermogenic properties in overweight adults

2013 68 participants 12 weeks Brown seaweed extract 5 g/day
Human Study RCT Positive

Study Type

Randomised Controlled Trial

Purpose

Assess brown algae thermogenic properties in overweight adults

Dose

Brown seaweed extract 5 g/day

Participants

68

Duration

12 weeks

Results

Fat oxidation significantly increased; RMR elevated; visceral fat reduced; fucoxanthin identified as key thermogenic compound

How They Measured It

RMR via indirect calorimetry, substrate oxidation, body composition

Read full study
9

Effects of dietary seaweed on obesity-related metabolic status: a systematic review and meta-analysis of randomized controlled trials

2025 ? participants See full study As per study protocol
Review/Other Positive

Study Type

Systematic review and meta-analysis

Purpose

Effects of dietary seaweed on obesity-related metabolic status: a systematic review and meta-analysis of randomized controlled trials

Dose

As per study protocol

Participants

See full study

Duration

See full study

Results

Statistically significant findings reported — see full study for complete results.

How They Measured It

See full study for endpoints and measurement methods

Read full study

Antioxidant Effects

3

Evaluate brown seaweed polyphenol (phlorotannin) antioxidant activity

2012 60 participants 8 weeks Phlorotannin-rich brown algae extract 1 g/day
Human Study RCT Positive

Study Type

Randomised Controlled Trial

Purpose

Evaluate brown seaweed polyphenol (phlorotannin) antioxidant activity

Dose

Phlorotannin-rich brown algae extract 1 g/day

Participants

60

Duration

8 weeks

Results

Significant increase in ORAC and FRAP; SOD and catalase activity elevated; MDA reduced by 25%

How They Measured It

ORAC, FRAP, plasma MDA, antioxidant enzyme activity

Read full study
4

Assess brown seaweed extract antioxidant capacity in adults

2015 75 participants 8 weeks Brown algae extract 2 g/day
Human Study RCT Positive

Study Type

Randomised Controlled Trial

Purpose

Assess brown seaweed extract antioxidant capacity in adults

Dose

Brown algae extract 2 g/day

Participants

75

Duration

8 weeks

Results

Antioxidant capacity significantly improved; oxidative stress markers reduced; consistent with phlorotannin and fucoxanthin activity

How They Measured It

Plasma antioxidant capacity, oxidative stress markers

Read full study

Anti-Inflammatory Effects

5

Evaluate brown seaweed extract on systemic inflammation

2008 65 participants 12 weeks Brown algae extract 3 g/day
Human Study RCT Positive

Study Type

Randomised Controlled Trial

Purpose

Evaluate brown seaweed extract on systemic inflammation

Dose

Brown algae extract 3 g/day

Participants

65

Duration

12 weeks

Results

CRP significantly reduced (−22%); IL-6 reduced (−18%); TNF-alpha reduced; arachidonic acid metabolite levels lowered

How They Measured It

CRP, IL-6, TNF-alpha, arachidonic acid metabolites

Read full study

Thyroid Support & Clinical Evidence

6

Review brown algae bioactive compounds and clinical health evidence

2017 140 participants Various Various
Human Study Mixed

Study Type

Systematic Review

Purpose

Review brown algae bioactive compounds and clinical health evidence

Dose

Various

Participants

140

Duration

Various

Results

Multiple bioactive classes in brown algae; strongest clinical evidence for antioxidant, anti-inflammatory, metabolic, and thyroid effects

How They Measured It

Narrative review of fucoxanthin, fucoidan, phlorotannins, iodine

Read full study
7

Evaluate brown seaweed bioactive fraction on thyroid support

2018 88 participants 12 weeks Brown algae 400 µg iodine equivalent
Human Study RCT Positive

Study Type

Randomised Controlled Trial

Purpose

Evaluate brown seaweed bioactive fraction on thyroid support

Dose

Brown algae 400 µg iodine equivalent

Participants

88

Duration

12 weeks

Results

Urinary iodine significantly increased; TSH normalised in deficient subjects; T3 elevated; metabolic rate improvement correlated with thyroid improvement

How They Measured It

TSH, T3, T4, metabolic rate, urinary iodine

Read full study
8

Assess brown seaweed extract for metabolic and antioxidant benefits

2018 46 participants 12 weeks Brown algae extract 4 g/day
Human Study RCT Mixed

Study Type

Randomised Controlled Trial

Purpose

Assess brown seaweed extract for metabolic and antioxidant benefits

Dose

Brown algae extract 4 g/day

Participants

46

Duration

12 weeks

Results

Comprehensive metabolic improvement; antioxidant capacity elevated; gut microbiome diversity increased; consistent multi-system benefit

How They Measured It

Metabolic markers, antioxidant capacity, body composition, gut health

Read full study

Frequently Asked Questions

Common questions about Brown Seaweed Extract research

What does the research say about Brown Seaweed Extract?

There are currently 9 peer-reviewed studies on Brown Seaweed Extract (Brown algae (Phaeophyceae) extract), involving 622 total participants. Research covers Metabolism, Antioxidant, Anti-Inflammatory and 1 more areas. The overall evidence strength is rated as Strong.

How strong is the evidence for Brown Seaweed Extract?

The evidence is currently rated as "Strong Evidence". This rating is based on study design quality (randomisation, blinding, placebo controls), sample sizes, study types (8 human studies), and reported outcomes.

What health goals has Brown Seaweed Extract been studied for?

Brown Seaweed Extract has been researched for: Metabolism, Antioxidant, Anti-Inflammatory, Thyroid Support. Each area has its own body of evidence which you can explore in the study breakdowns above.

Are the studies on Brown Seaweed Extract based on human trials?

Yes, 8 out of 9 studies are human trials. Human trials carry more weight in our evidence scoring system.